All specialties - British Journal of Surgery

Scientific Surgery

Adjuvant nivolumab in resected esophageal or gastroesophageal junction cancer. N Engl J Med 2021; 384: 1191-1203.

Authors: Kelly RJ, Ajani JA, Kuzdzal J, Zander T, van Cutsem E, Piessen G et al.

Scientific Surgery

Meta-analysis and trial sequential analysis of randomized controlled trials comparing high and low ligation of the inferior mesenteric artery in rectal cancer surgery. Dis Colon Rectum 2020; 63: 988-999.

Authors: Hajibandeh S, Hajibandeh S, Maw A

Scientific Surgery

Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial. Gut 2020; 69: 1492-1501.

Authors: Kudo M, Ueshima K, Ikeda M, Torimura T, Tanebe N, Aikata H et al.

Scientific Surgery

Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open label, phase 3 trial. Lancet Oncol 2021; 22: 256-266.

Authors: Quenet F, Elias D, Roca L, Goere D, Ghouti L, Pocard M et al.

Scientific Surgery

Early complications in delayed breast reconstruction: A prospective, randomized study comparing different reconstructive methods in radiated and non-radiated patients. Eur J Surg Oncol 2020; 46: 2208-2217.

Authors: Brorson F, Thorarinsson A, Kolby L, Elander A, Hansson E

Scientific Surgery

Effect of capecitabine maintenance therapy using lower dosage and higher frequency vs observation on disease-free survival among patients with early-stage triple-negative breast cancer who had received standard treatment. The SYSUCC-001 Randomized Clinical Trial. JAMA 2021; 325: 50-58.

Authors: Wang X, Wang S-S, Huang H, Cai L, Peng R-J, Lin Y et al.

Scientific Surgery

Simultaneous versus delayed resection for initially resectable synchronous colorectal cancer liver metastases. A prospective, open-label, randomized, controlled trial. Ann Surg 2021; 273: 49-56.

Authors: Boudjema K, Locher C, Sabbagh C, Ortega-Deballon P, Heyd B, Bachellier P et al.

Scientific Surgery

Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials. Lancet Oncol 2020; 21: 1620-1629.

Authors: Andre T, Meyerhardt J, Iveson T, Sobrero A, Yoshino T, Souglakos I et al.

Scientific Surgery

Long-term oncologic results after stenting as a bridge to surgery versus emergency surgery for malignant left-sided colonic obstruction. A multicenter randomized controlled trial (ESCO Trial). Ann Surg 2020; 272: 703-708.

Authors: Arezzo A, Forcignanò E, Bonino MA, Balagué C, Targarona E, Borghi F et al.

Scientific Surgery

Safety and efficacy of indocyanine green tracer-guided lymph node dissection during laparoscopic radical gastrectomy in patients with gastric cancer. A randomized clinical trial. JAMA Surg 2020; 155: 300-311.

Authors: Chen Q-Y, Xie J-W, Zhong Q, Wang J-B, Lin J-X, Lu J et al.

Scientific Surgery

Surgical morbidity and mortality from the multicenter randomized controlled NeoRes II Trial. Standard versus prolonged time to surgery after neoadjuvant chemoradiotherapy for esophageal cancer. Ann Surg 2020; 272: 684-689.

Authors: Nilsson K, Klevebro F, Rouvelas I, Lindblad M, Szabo E, Halldestam I et al.

Scientific Surgery

Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised double-blind, phase 3 trial. Lancet 2020; 396: 1090-1100.

Authors: Mittendorf EA, Zhang H, Barrios CH, Saji S, Jung KH, Hegg R et al.

Scientific Surgery

Adjuvant 131I-metuximab for hepatocellular carcinoma after liver resection: a randomised, controlled, multicentre, open-label, phase 2 trial. Lancet Gastroenterol Hepatol 2020; 5: 548-560.

Authors: Li J, Xing J, Yang Y, Liu J, Wang W, Xia Y et al.

Scientific Surgery

Efficacy and safety of tailored and dose‐dense adjuvant chemotherapy and trastuzumab for resected HER2‐positive breast cancer: Results from the phase 3 PANTHER trial. Cancer 2020; 126: 1175-1182.

Authors: Papakonstantinou A, Matikas A, Bengtsson NO, Malmstrom P, Hedayati E, Steger G et al.

Scientific Surgery

Five-year analysis of adjuvant dabrafenib plus trametinib in Stage III Melanoma. N Engl J Med 2020; 383: 1139-1148.

Authors: Dummer R, Hauschild A, Santinami M, Atkinson V, Mandala M, Kirkwood JM et al.

Scientific Surgery

A randomized controlled clinical trial. No clear benefit to prophylactic central neck dissection in patients with clinically node negative papillary thyroid cancer. Ann Surg 2020; 272: 496-503.

Authors: Sippel RS, Robbins SE, Poehls JL, Pitt SC, Chen H, Leverson G et al.

Scientific Surgery

Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial. Lancet Gastroenterol Hepatol 2020; 5: 465-474.

Authors: Rullier E, Vendrely V, Rouanet P, Tuech JJ, Valverde A

Scientific Surgery

Phase III randomized trial of bisphosphonates as adjuvant therapy in breast cancer: S0307. J Natl Cancer Inst 2020; 112: 698-707.

Authors: Gralow JR, Barlow WE, Paterson AHG, M’iao JL, Lew DL, Stopeck AT et al.

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