This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Cost‐effectiveness of laparoscopic fundoplication versus continued medical management for the treatment of gastro‐oesophageal reflux disease based on long‐term follow‐up of the REFLUX trial. BJS 2013; 100: 1205-1213.
Published: 17th June 2013
Authors: R. Faria, L. Bojke, D. Epstein, B. Corbacho, M. Sculpher
Background
Laparoscopic fundoplication surgery has been shown to be a cost‐effective alternative to continued medical management over 1 year for patients with gastro‐oesophageal reflux disease (
Method
Individual patient data were used from the 5‐year follow‐up of the
Results
The group randomized to surgery experienced better health outcomes in each year of follow‐up, but the difference narrowed over time. At 5 years, the surgery group had experienced 0·216 (95 per cent confidence interval 0·021 to 0·412) more
Conclusion
Laparoscopic fundoplication is a cost‐effective alternative to continued medical management over 5 years. No evidence was found to suggest that the cost‐effectiveness of laparoscopic fundoplication diminishes over time.
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