This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Determinants of improved survival after oesophagectomy for cancer. BJS 2015; 102: 668-675.
Published: 18th March 2015
Authors: A. K. Talsma, R. A. M. Damhuis, E. W. Steyerberg, C. Rosman, J. J. B. van Lanschot, B. P. L. Wijnhoven et al.
Background
Survival after oesophagectomy for cancer seems to be improving. This study aimed to identify the most important contributors to this change.
Method
Patients who underwent oesophagectomy from 1999 to 2010 were extracted from the Netherlands Cancer Registry. Four time periods were compared: 1999–2001 (period 1), 2002–2004 (period 2), 2005–2007 (period 3) and 2008–2010 (period 4). Hospital type, tumour location, tumour type, tumour differentiation, neoadjuvant therapy, operation type, (y)
Results
A total of 4382 patients were identified. Two‐year overall survival rates improved from 49·3 per cent in period 1 to 58·4, 56·2 and 61·0 per cent in periods 2, 3 and 4 respectively (
Conclusion
The observed increase in long‐term survival after surgery for oesophageal cancer between 1999 and 2010 in the Netherlands is difficult to explain fully, although the recent increase seems to be partly attributable to the introduction of neoadjuvant therapy.
Full textYou may also be interested in
Randomized clinical trial
Authors: K. Misawa, Y. Mochizuki, M. Sakai, H. Teramoto, D. Morimoto, H. Nakayama et al.
Randomized clinical trial
Authors: R. J. Hopkins, T. Irvine, G. G. Jamieson, P. G. Devitt, D. I. Watson
Randomized clinical trial
Authors: B. Sunde, F. Klevebro, A. Johar, G. Johnsen, A.‐B. Jacobsen, N. I. Glenjen et al.
Original article
Authors: Y. Baba, T. Yagi, K. Kosumi, K. Okadome, D. Nomoto, K. Eto et al.
Original article
Authors: Å. A. Fretland, V. J. Dagenborg, G. M. Waaler Bjørnelv, D. L. Aghayan, A. M. Kazaryan, L. Barkhatov et al.
Original article
Authors: J. A. Elliott, L. O'Byrne, G. Foley, C. F. Murphy, S. L. Doyle, S. King et al.
Original article
Authors: W. H. Allum, E. C. Smyth, J. M. Blazeby, H. I. Grabsch, S. M. Griffin, S. Rowley et al.
Systematic review
Authors: N. Moody, A. Adiamah, F. Yanni, D. Gomez
Article
Authors: Y. Y. Broza, S. Khatib, A. Gharra, A. Krilaviciute, H. Amal, I. Polaka et al.
Original article
Authors: S. Ahlin, C. Cefalù, I. Bondia‐Pons, E. Capristo, L. Marini, A. Gastaldelli et al.
Original article
Authors: A.‐H. Chen, W.‐H. Chan, Y.‐H. Lee, J.‐H. Tseng, T.‐S. Yeh, C.‐T. Chiu et al.
Original article
Authors: J. X. Lin, C. Yoon, J. Desiderio, B. C. Yi, P. Li, C. H. Zheng et al.