This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Outcome after restorative proctocolectomy and ileal pouch–anal anastomosis in children and adults. BJS 2017; 104: 1640-1647.
Published: 20th September 2017
Authors: K. Diederen, S. S. Sahami, M. M. Tabbers, M. A. Benninga, A. Kindermann, P. J. Tanis et al.
Background
Studies comparing the outcome of ileal pouch–anal anastomosis (IPAA) in children and adults are scarce. This complicates decision‐making in young patients. The aim of this study was to compare adverse events and pouch function between children and adults who underwent IPAA.
Method
This cross‐sectional cohort study included all consecutive children (aged less than 18 years) and adults with a diagnosis of inflammatory bowel disease or familial adenomatous polyposis who underwent IPAA in a tertiary referral centre between 2000 and 2015. Adverse events were assessed by chart review, and pouch function by interview using a pouch function score (PFS).
Results
In total, 445 patients underwent IPAA: 41 children (median age 15 years) and 404 adults (median age 39 years), with a median follow‐up of 22 (i.q.r. 8–68) months. Being overweight (
Conclusion
Long‐term pouch failure rates and pouch function were similar in children and adults. There is no need for a more cautious attitude to use of IPAA in children based on concerns about poor outcome.
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