This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Role of micro‐RNAs in breast cancer surgery. BJS 2018; 105: e19-e30.

Published: 17th January 2018

Authors: P. McAnena, A. Lowery, M. J. Kerin

Background

The management of breast cancer has changed dramatically in the molecular era. Micro‐RNAs can contribute to multiple facets of cancer surgery.

Method

This narrative review, based on years of research on the role of micro‐RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.

Results

Micro‐RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.

Conclusion

The molecular era has changed understanding of cancer. Micro‐RNAs have the potential for use in personalized cancer strategies.

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