Leser–Trélat sign (November 2022 [2])

Published: 04/05/2023

Authors: Shang-Wei Lin and Jian-Han Chen

An 80-year-old man presented as an emergency with a pneumoperitoneum. He was noted to have seborrhoeic keratoses on his chest bilaterally, his right axilla, and pubic regions that had developed in the month before admission. He was found to have metastatic sigmoid adenocarcinoma with liver metastases. The Leser–Trélat sign describes the eruption of multiple seborrhoeic keratoses secondary to disseminated malignancy.