Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Cytosponge-trefoil factor 3 versus usual care to identify Barrett’s oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial. Lancet 2020; 396: 333-344.

Authors: Fitzgerald RC, di Pietro M, O’Donovan M, Maroni R, Muldrew B, Debiram-Beeecham I et al.

Scientific Surgery

Cost-effectiveness of laparoscopic ileocaecal resection versus infliximab treatment of terminal ileitis in Crohn’s disease: the LIR!C Trial. Gut 2019; 68: 1774-1780

Authors: De Groof EJ, Stevens TW, Eshuis EJ, Gardenbroek TJ, Bosmans JE, van Dongen JM et al.

Scientific Surgery

Endoscopic or surgical myotomy in patients with idiopathic achalasia. N Engl J Med 2019; 381: 2219-2229

Authors: Werner YB, Hakanson B, Martinek J, Repici A, von Rahden BHA, Bredenoord AJ et al.

Scientific Surgery

Comparison of laparoscopic 2700 posterior partial fundoplication vs total fundoplication for the treatment of gastroesophageal reflux disease. A randomized clinical trial. JAMA Surg 2019; 154: 479-486

Authors: Håkanson BS, Lundell L, Bylund A, Thorell A

Scientific Surgery

Randomized trial of medical versus surgical treatment for refractory heartburn. N Engl J Med 2019; 381: 1513-1523

Authors: Spechler SJ, Hunter JG, Jones KM, Lee RL, Smith BR, Mashimo H et al.

Scientific Surgery

Randomized trial of division versus nondivision of short gastric vessels during Nissen fundoplication: 20-year outcomes. Ann Surg 2018; 268: 228-232.

Authors: Kinsey-Trotman SP, Devitt PG, Bright T, Thompson SK, Jamieson GG, Watson DI et al.

Scientific Surgery

Esomeprazole and aspirin in Barrett’s oesophagus (AspECT): a randomised factorial trial. Lancet 2018; 392: 400–8.

Authors: Jankowski JAZ, de Caestecker J, Love SB, Reilly G, Watson P, Sanders S et al.

Scientific Surgery

A randomised trial of endoscopic submucosal dissection versus endoscopic mucosal resection for early Barrett’s neoplasia. Gut 2017; 66: 783-793.

Authors: Terheggen G, Horn EM, Vieth M, Gabbert H, Enderle M, Neugebauer A et al.

Scientific Surgery

Seventeen-year outcome of a randomized clinical trial comparing laparoscopic and conventional Nissen fundoplication: a plea for patient counseling and clarification. Ann Surg 2017; 266: 23-28.

Authors: Oor J, Roks D, Broeders J, Hazebroek E, Gooszen H

Scientific Surgery

Long-term results of the European achalasia trial: a multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy. Gut 2016; 65: 732-739.

Authors: Moonen A, Annese V, Belmans A, Bredenoord AJ, des Varannes SB, Costantini M et al.

Scientific Surgery

Laparoscopic mesh-augmented hiatoplasty with cardiophrenicopexy versus laparoscopic Nissen fundoplication for the treatment of gastroesophageal reflux disease: a double-center randomized controlled trial. Ann Surg 2015; 262: 721–727.

Authors: Müller-Stich B, Linke G, Senft J, Achtstätter V, Müller P, Diener M et al. et al.

Scientific Surgery

Comparative study between laparoscopic Heller Myotomy versus pneumatic dilatation for treatment of early achalasia: a prospective randomized study. J Lap Adv Surg Tech A 2015, 25: 460-464.

Authors: Hamdy E, El Nakeeb A, El Hanfy E, El Hemaly M, Salah T, Hamed H et al. et al.

Scientific Surgery

Robotic Nissen fundoplication for gastroesophageal reflux disease: a meta-analysis of prospective randomized controlled trials. Surg Today 2014; 44: 1415-1423.

Authors: Yao G, Liu K, Fan Y

Scientific Surgery

Radiofrequency ablation vs. endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia. A randomized clinical trial. JAMA 2014; 311: 1209-1217.

Authors: Phao KN, van Vilsteren FGI, Weusten BLAM, Bisschops R, Schoon EJ, Ragunath K et al. et al.

Scientific Surgery

Efficacy and safety of lesogaberan in gastro-oesophageal reflux disease: a randomised controlled trial. Gut 2013; 62: 1248–1255.

Authors: Shaheen NJ, Denison H, Bjorck K, Karlsson M, Silberg DG

Scientific Surgery

Laparoscopic anterior 180-degree versus Nissen fundoplication for gastroesophageal reflux disease: systematic review and meta-analysis of randomized clinical trials. Ann Surg 2013; 257: 850-859.

Authors: Broeders J, Roks DJ, Ahmed AU, Watson DI, Baigrie RJ, ZhanGuo C et al. et al.

Scientific Surgery

Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX). BMJ 2013; 346: f1908.

Authors: Grant AM, Cotton SC, Boachie C, Ramsay CR, Krukowski ZH, Heading RC et al. et al.

Scientific Surgery

Meta-analysis of robot-assisted versus conventional laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease. ANZ J Surg 2012; 82: 112-117.

Authors: Wang Z, Zheng Q, Jin Z

Scientific Surgery

Five-year outcome after laparoscopic anterior partial versus Nissen fundoplication: four randomized trials. Ann Surg 2012; 255: 637–642.

Authors: Broeders JA, Roks DJ, Jamieson GG, Devitt PG, Baigrie RJ, Watson DI et al.

Scientific Surgery

Biologic prosthesis to prevent recurrence after laparoscopic paraesophageal hernia repair: long-term follow-up from a multicenter, prospective, randomised trial. J Am Coll Surg 2011; 213: 461-468.

Authors: Oelschlager BK, Pellegrini CA, Hunter JG, Brunt ML, Soper NJ, Sheppard BC et al.

Scientific Surgery

Clinical outcome of a randomized controlled blinded trial of open versus laparoscopic Nissen fundoplication in infants and children. Ann Surg 2011; 254: 209-216.

Authors: McHoney M, Wade A, Eaton S, Howard R, Kiely E, Drake D et al. et al.

Scientific Surgery

Laparoscopic anterior versus posterior fundoplication for gastroesophageal reflux disease: systematic review and meta-analysis of randomised clinical trials. Ann Surg 2011; 254: 39–47.

Authors: Broeders J, Roks DJ, Ahmed Ali U, Draaisma WA, Smout AJ, Hazebroek EJ. et al.

Scientific Surgery

Stepwise radical endoscopic resection versus radiofrequency ablation for Barrett’s oesophagus with high-grade dysplasia or early cancer: a multicentre randomised trial. Gut 2011; 60: 765–773.

Authors: van Vilsteren FGI, Pouw RE, Seewald S, Herrero LA, Sondermeijer CMT, Visser M et al.

Scientific Surgery

Meta-analysis of laparoscopic total (Nissen) versus posterior (Toupet) fundoplication for gastro-oesophageal reflux disease based on randomized clinical trials. ANZ J Surg 2011; 81: 246–252.

Authors: Tan G, Yang Z, Wang Z.

Scientific Surgery

Total or posterior partial fundoplication in treatment of GERD: results of a randomized trial after 2 decades of follow up. Ann Surg 2011; 253: 875–878.

Authors: Mardani J, Lundell L, Engstrom C.

Scientific Surgery

Nissen versus Dor fundoplication for treatment of gastroesophageal reflux disease: a blinded randomised clinical trial. Digest Surg 2011; 28: 80–86.

Authors: Raue W, Ordermann J, Jacobi CA, Menenakos C, Buchholz A, Hartmann J. et al.

Scientific Surgery

Laparoscopic antireflux surgery vs. esomeprazole treatment for chronic GERD: the LOTUS randomised clinical trial. JAMA 2011; 305: 1969–1677.

Authors: Galmiche JP, Hatlebakk J, Attwood S, Ell C, Fiocca R, Eklund S et al.

Scientific Surgery

Long-term outcome of laparoscopic Nissen fundoplication compared with laparoscopic Thal fundoplication in children: a prospective randomized study. Ann Surg 2011; 253: 44–49.

Authors: Rainer K, Andrews J, Grant H.

Scientific Surgery

Randomized controlled trial of laparoscopic anterior versus posterior fundoplication for gastro-oesophageal reflux disease. ANZ J Surg 2010; 80: 500–505.

Authors: Khan M, Smythe A, Globe J, Stoddard CJ, Ackroyd R.

Scientific Surgery

Endoscopic cyanoacrylate injection versus beta blocker for secondary prophylaxis of gastric variceal bleed: a randomised controlled trial. Gut 2010; 59: 729-735.

Authors: Mishra SJ, Sharma BC, Kumar A, Sarin SK.

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