Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Efficacy and safety of using dual versus monotherapy antiplatelet agents in secondary stroke prevention: systematic review and meta-analysis of randomized controlled clinical trials. Circulation 2021; 143: 2441–2453.

Authors: Trifan G, Gorelick PB, Testai FD

Scientific Surgery

Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy. Lancet 2021; 398: 1065-1073.

Authors: Halliday A, Bulbia R, Bonati LH, Chester J, Cradduck-Bamford A, Peto R et al.

Scientific Surgery

Network meta-analysis of carotid endarterectomy closure Techniques. Eur J Vasc Endovasc Surg 2021; 61: 181-190.

Authors: Lazarides MK, Christaina E, Argyriou C, Georgakarakos E, Tripsianis G, Georgiadis GS et al.

Scientific Surgery

Overview of primary and secondary analyses from 20 randomised controlled trials comparing carotid artery stenting with carotid endarterectomy. Eur J Vasc Endovasc Surg 2019; 58: 479-493

Authors: Batchelder AJ, Saratzis A, Naylor AR

Scientific Surgery

Overview of primary and secondary analyses from 20 randomised controlled trials comparing carotid artery stenting with carotid endarterectomy. Eur J Vasc Endovasc Surg 2019; 58: 479-493

Authors: Batchelder A, Saratzis A, Naylor AR

Scientific Surgery

Antiplatelet therapy vs anticoagulation therapy in cervical artery dissection. The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial final results. JAMA Neurol 2019; 76: 657-664.

Authors: Markus HS, Levi C, King A, Madigan J, Norris J, et al. for the et al.

Scientific Surgery

Optimal antiplatelet therapy in moderate to severe asymptomatic carotid stenosis: a comprehensive review of the literature. Eur J Vasc Endovasc Surg 2019; 57: 199-211.

Authors: Murphy SJ, Naylor AR, Ricco J-B, Sillesen H, Kakkos S, Halliday H et al.

Scientific Surgery

A meta-analysis of randomized trials comparing bovine pericardium and other patch materials for carotid endarterectomy. J Vasc Surg 2018; 68: 1241–1256.

Authors: Texakalidis P, Giannopoulos S, Charisis N, Giannopoulos S, Karasavvidis T, Koullias G et al.

Scientific Surgery

Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high-risk transient ischaemic attack. BMJ 2018; 363: k5108.

Authors: Hao Q, Tampi M, O’Donnell M, Foroutan F, Siemieniuk RAC, Guyatt G et al.

Scientific Surgery

Safety of stenting and endarterectomy for asymptomatic carotid artery stenosis: a meta-analysis of randomised controlled trials. Eur J Vasc Endovasc Surg 2018; 55: 614-624.

Authors: Cui L, Han Y, Zhang S, Liu X, Zhang J

Scientific Surgery

Safety and efficacy of remote ischemic preconditioning in patients with severe carotid artery stenosis before carotid artery stenting. A proof-of-concept, randomized controlled trial. Circulation 2017; 135: 1325-1335.

Authors: Zhao W, Meng R, Ma C, Hou B, Jiao L, Zhu F et al.

Scientific Surgery

Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials. Lancet 2016; 387: 1305-1311.

Authors: Howard G, Roubin GS, Jansen O, Hendrikse J, Halliday A, Fraedrich G et al.

Scientific Surgery

Long-term results of stenting versus endarterectomy for carotid artery stenosis. N Engl J Med 2016; 374: 1021-1031.

Authors: Brott TG, Howard G, Roubin GS, Meschia JF, Mackey A, Brooks W et al.

Scientific Surgery

Randomized trial of stent versus surgery for asymptomatic carotid stenosis. N Engl J Med 2016; 374: 1011-1020.

Authors: Rosenfield K, Matsumura JS, Chaturvedi S, Riles T, Ansel GM, Metzger C et al.

Scientific Surgery

Pioglitazone after ischemic stroke or transient ischemic attack. N Engl J Med 2016; 374: 1321-1331.

Authors: Kernan WN, Viscoli CM, Furie KM, Young LH, Inzucchi SE, Gorman M et al.

Scientific Surgery

Clopidogrel with aspirin in acute minor stroke or transient ischemic attack (CHANCE) trial. Circulation. 2015; 132: 2-3.

Authors: Wang Y, Pan Y, Zhao X, Li H, Wang D, Claiborne Johnston S et al. on behalf of the CHANCE Investigators et al.

Scientific Surgery

Long term results from a randomized controlled trial analyzing the role of systematic preoperative coronary angiography before elective carotid endarterectomy in patients with asymptomatic coronary artery disease. Eur J Vasc Endovasc Surg 2015; 49: 366-374.

Authors: Illuminati G, Schneider F, Greco C, Mangieri E, Schiariti M, Tanzilli G et al. et al.

Scientific Surgery

Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial. Lancet 2015; 385: 529–538.

Authors: Bonati LH, Dobson J, Featherstone RL, Ederle J, van der Worp HB, de Borst GJ et al. et al.

Scientific Surgery

High versus standard clopidogrel loading in patients undergoing carotid artery stenting prior to cardiac surgery to assess the number of microemboli detected with transcranial Doppler: results of the IMPACT trial. J Cardiovasc Surg 2013; 54: 337-347.

Authors: Van der Hayden J, van Werkum J, Hackeng C, Kelder JC, Breet NJ, Deneer VH et al. et al.

Scientific Surgery

Randomized clinical trial of open-cell vs. closed-cell stents for carotid stenting and effects of stent design on cerebral embolization. J Vasc Surg 2011; 54: 1310-1316.

Authors: Timaran CH, Rosero EB, Higuera A, Ilarraza A, Modrall JG, Clagett PG et al.

Scientific Surgery

Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischaemia: the Carotid Occlusion Surgery Study randomized trial. JAMA 2011; 306: 1983-1992.

Authors: Powers WJ, Clarke WR, Grubb RL Jr, Videen TO, Adams HP Jr, Derdeyn CP et al.

Scientific Surgery

Short-term results of a randomised trial examining timing of carotid endarterectomy in patients with severe asymptomatic unilateral carotid stenosis undergoing carotid artery bypass grafting. J Vasc Surg 2011; 54: 993–999.

Authors: lluminati G, Ricco JB, Calio F, Pacile MA, Mirald F, Frati G et al.

Scientific Surgery

Safety of stenting and endarterectomy by symptomatic status in the carotid revascularization endarterectomy versus stenting trial (CREST). Stroke 2011; 42: 675–680.

Authors: Silver FL, Mackey A, Clark WM, Brooks W, Timaran CH, Chiu D et al et al.

Scientific Surgery

A systematic review and meta-analysis of randomized trials of carotid endarterectomy vs. stenting. J Vasc Surg 2011; 53: 792-797.

Authors: Murad MH, Shahrour A, Shah ND, Monton VM, Ricotta JJ.

Scientific Surgery

Age modifies the relative risk of stenting versus endarterectomy for symptomatic carotid stenosis – a pooled analysis of EVA-3S, SPACE, and ICSS. Eur J Vasc Endovasc Surg 2011; 41: 153–158.

Authors: Bonati LH, Fraedrich G on behalf of the Carotid Stenting Trialists’ Collaboration.

Scientific Surgery

Heparin versus bivalirudin for carotid artery stenting using proximal endovascular clamping for neuroprotection: results from a prospective randomized study. J Vasc Surg 2010; 52: 1505–1510.

Authors: Stabile E, Sorropago G, Tesorio T, Popusoi G, Ambrosini V, Mottola MT et al. et al.

Scientific Surgery

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. Lancet 2010; 376: 1074-1084.

Authors: Halliday A, Harrison M, Hayter E, Kong X, Mansfield A, Marro J et al. et al.

Scientific Surgery

Short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis: a preplanned meta-analysis of individual patient data. Lancet 2010; 376: 1062-1073.

Authors: Carotid Stenting Trialists’ Collaboration.

Scientific Surgery

Early versus delayed carotid endarterectomy after a nondisabling ischemic stroke: a prospective randomized study. Surgery 2002; 131: 287-93.

Authors: Ballotta E, Da Giau G, Baracchini C, Abbruzzese E, Saladini M, Meneghetti G. et al.

Scientific Surgery

Prospective randomised trial of routine versus selective shunting in carotid endarterectomy based on stump pressure. J Vasc Surg 2010; 51: 1133–1138.

Authors: AbuRahma AF, Stone PA, Hass SM, Dean LS, Habib J, Keiffer T et al. et al.

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