Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Initial laparotomy versus peritoneal drainage in extremely low birthweight infants with surgical necrotizing enterocolitis or isolated intestinal perforation. A multicenter randomized clinical trial. Ann Surg 2021; 274: e370-e380.

Authors: Blakely M, Tyson JE, Lally KP, Hintz SR, Eggleston B, Stevenson DK et al.

Scientific Surgery

Randomized controlled study investigating the effect of a dedicated in-house art gallery on the recovery of patients after major oncologic surgery. Ann Surg 2021; 274: 264-270.

Authors: Lone Z, Hussein AA, Khan H, Steele M, Jing Z, Attwood K et al.

Scientific Surgery

Effect of a predictive model on planned surgical duration accuracy, patient wait time, and use of presurgical resources. A randomized clinical trial. JAMA Surg 2021; 156 :315-321.

Authors: Strömblad CT, Baxter-King R, Meisami A, Yee S-J, Levine MR, Ostrovsky A et al.

Scientific Surgery

Simple wound Irrigation in the postoperative treatment for surgically drained spontaneous soft tissue abscesses: a prospective, randomized controlled trial. World J Surg 2020; 44: 4041-4051.

Authors: Oehme F, Ruhle A, Bornert K, Hempel S, Link B-C, Babst R et al.

Scientific Surgery

Effect of e-cigarettes plus counseling vs counseling alone on smoking cessation. A randomized clinical trial. JAMA 2020; 324: 1844-1854.

Authors: Eisenberg MJ, Hébert-Losier A, Windle SB, Greenspoon T, Brandys T, Fülöp T et al.

Scientific Surgery

Telemedicine to follow patients in a general surgery department. A randomized controlled trial. Am J Surg 2020; 219: 882-887.

Authors: Cremades M, Ferret G, Pares D, Navines J, Espin F, Pardo F et al.

Scientific Surgery

A randomized, double‐blind, placebo‐controlled trial of probiotics to reduce the severity of oral mucositis induced by chemoradiotherapy for patients with nasopharyngeal carcinoma. Cancer 2019; 125: 1081-1090

Authors: Jiang C, Wang H, Xia C, Dong Q, Chen E, Qiu Y et al.

Scientific Surgery

A preventive program for work-related musculoskeletal disorders among surgeons. Outcomes of a randomized controlled clinical trial. Ann Surg 2019; 270: 969-975

Authors: Giagio S, Volpe G, Pillastrini P, Gasparre G, Frizziero A, Squizzato F et al.

Scientific Surgery

Anaesthetic depth and complications after surgery: an international randomized controlled trial. Lancet 2019; 394: 1907-1914

Authors: Short TG, Campbell D, Frampton C, Chan MTV, Myles PS, Corcoran TB et al.

Scientific Surgery

Omadacycline for acute bacterial skin and skin-structure infections. N Engl J Med 2019; 380: 517-527.

Authors: O’Riordan W, Green S, Overcash JS, Puljiz I, Metallidis S, Gardovskis J et al.

Scientific Surgery

Sorafenib for advanced and refractory desmoid tumors. N Engl J Med 2018; 379: 2417-2428.

Authors: Gounder MM, Mahoney MR, Van Tine BA, Ravi V, Attia S, Deshpande HA et al.

Scientific Surgery

Treatments of primary basal cell carcinoma of the skin: a systematic review and network meta-analysis. Ann Intern Med. 2018; 169: 456-466.

Authors: Drucker AM, Adam GP, Rofeberg V, Gazula A, Smith B, Moustafa A et al.

Scientific Surgery

Personalised perioperative care by e-health after intermediate-grade abdominal surgery: a multicentre, single-blind, randomised, placebo-controlled trial. Lancet 2018; 392: 51-59.

Authors: Van der Meil E, Anema JR, Leclercq WKG, Bongers MY, Meijerink WJHJ, Bonjer HJ et al.

Scientific Surgery

Sutureless vs sutured gastroschisis closure: a prospective randomized controlled trial. J Am Coll Surg 2017; 224: 1091-1096.

Authors: Bruzoni M, Jaramillo JD, Dunlap JL, Abrajano C, Stack SW, Hintz SR et al.

Scientific Surgery

Effect of oral capsule vs. colonoscopy-delivered fecal microbiota transplantation on recurrent Clostridium difficile infection. A randomized clinical trial JAMA 2017; 318: 1985-1993.

Authors: Kao D, Roach B, Silva M, Beck P, Rioux K, Kaplan GG et al.

Scientific Surgery

Use of water-soluble contrast medium (gastrografin) does not decrease the need for operative intervention nor the duration of hospital stay in uncomplicated acute adhesive small bowel obstruction? A multicenter, randomized, clinical trial (Adhesive Small Bowel Obstruction Study) and systematic review. Surgery 2017; 161: 1315–1325.

Authors: Scotté M, Mauvais F, Bubenheim M, Cossé C, Suaud L, Savoye-Collet C et al.

Scientific Surgery

Effect of an immersive preoperative virtual reality experience on patient reported outcomes: a randomized controlled trial. Ann Surg 2017; 265: 1068-1073.

Authors: Bekelis K, Calnan D, Simmons N, MacKenzie T, Kakoulides G

Scientific Surgery

Effect of cephalexin plus trimethoprim-sulfamethoxazole vs cephalexin alone on clinical cure of uncomplicated cellulitis. A randomized clinical trial. JAMA. 2017; 317: 2088-2096.

Authors: Moran GJ, Krishnadasan A, Mower WR, Abrahamian FM, LoVecchio F, Steele MT et al.

Scientific Surgery

Patient Hand-Off iNitiation and Evaluation (PHONE) study: a randomized trial of patient handoff methods. Am J Surg 2017; 213: 299-306.

Authors: Clanton J, Gardner A, Subichin M, McAlvanah P, Hardy W, Shah A et al.

Scientific Surgery

Transareolar single-port needlescopic thoracic sympathectomy under intravenous anesthesia without intubation: a randomized controlled trial. J Laparoendosc Adv Surg Tech 2016; 26: 958-964.

Authors: Chen J, Du Q, Lin M, Lin J, Li X, Lai F et al.

Scientific Surgery

Double-gloving impairs the quality of surgical knot tying: A randomised controlled trial. World J Surg 2016; 40: 2598–2602.

Authors: Battersby CLF, Battersby NJ, Hollyman M, Hunt JA

Scientific Surgery

Glove perforation rate in surgery: a randomized, controlled study to evaluate the efficacy of double gloving. Surg Infect 2016; 17: 436-442.

Authors: Makama JG, Okeme IM, Makama EJ, Ameh EA

Scientific Surgery

Two phase 3 trials of adalimumab for hidradenitis suppurativa. N Engl J Med 2016; 375: 422-434.

Authors: Kimball AB, Okun MM, Williams DA, Gottlieb AB, Papp KA, Zouboulis CC et al.

Scientific Surgery

Remote ischemic preconditioning to reduce contrast-induced nephropathy: a randomized controlled trial. Eur J Vasc Endovasc Surg 2015; 50: 527-532.

Authors: Menting TP, Sterenborg TB, de Waal Y, Donders R, Wever KE, Lemson MS et al. et al.

Scientific Surgery

Prospective randomized controlled trial comparing the effects of noncontact low-frequency ultrasound with standard care in healing split-thickness donor sites. J Am Coll Surg 2015; 221: 309–318.

Authors: Prather JL, Tummel EK, Patel AB, Smith DJ, Gould LJ

Scientific Surgery

A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention. N Engl J Med 2015; 373: 1618-1626.

Authors: Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA et al. et al.

Scientific Surgery

Pain SoluTions In the Emergency Setting (PASTIES) – patient-controlled analgesia versus routine care in emergency department patients with non-traumatic abdominal pain: randomised trial. BMJ 2015; 350: h3147.

Authors: Smith JE, Rockett M, Creanor S, Squire R, Hayward C, Ewings P et al.

Scientific Surgery

Integrated collaborative care for comorbid major depression in patients with cancer (SMaRT Oncology-2): a multicentre randomised controlled effectiveness trial. Lancet 2014; 384: 1099-1108.

Authors: Sharpe M, Walker J, Hansen CH, Martin P, Symeonides S, Gourley C et al. et al.

Scientific Surgery

A novel drug for the treatment of necrotizing soft-tissue infections. A randomized clinical trial. JAMA Surg 2014; 149: 528-536.

Authors: Bulger EM, Maier RV, Sperry J, Joshi M, Henry S, Moore FA et al. et al.

Scientific Surgery

Hypercapnia and acidosis during open and thoracoscopic repair of congenital diaphragmatic hernia and esophageal atresia: results of a pilot randomised controlled trial. Ann Surg 2013; 258: 895–900.

Authors: Bishay M, Giacomello L, Retrosi G, Thypoka M, Garroboli M, Brierley J et al. et al.

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