Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Abelacimab for prevention of venous thromboembolism. N Engl J Med 2021; 385: 609-617.

Authors: Verhamme P, Yi BA, Segers A, Salter J, Bloomfield D, Buller HR et al.

Scientific Surgery

Intermittent pneumatic compression in addition to standard prophylaxis of postoperative venous thromboembolism in extremely high-risk patients (IPC SUPER): a randomized controlled trial. Ann Surg 2021; 274: 63-69.

Authors: Lobastov K, Sautina E, Alencheva E, Bargandzhiya A, Schastlivtsev I, Barinov V et al.

Scientific Surgery

Five-year extension study of patients from a randomized clinical trial (VeClose) comparing cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vasc Surg Venous Lymphatic 2020; 8: 978-989.

Authors: Morrison N, Gibson K, Vasquez M, Weiss R, Jones A

Scientific Surgery

Randomized controlled trial of compression after endovenous thermal ablation of varicose veins (COMETA Trial). Ann Surg 2021; 273: 232-239.

Authors: Bootun R, Belramman A, Bolton-Saghdaoui L, Lane T, Riga C, Davies A et al.

Scientific Surgery

Long-term clinical and cost-effectiveness of early endovenous ablation in venous ulceration. A randomized clinical trial. JAMA Surg 2020; 155: 1113-1121.

Authors: Gohel M, Mora J, Szigeti M, Epstein DM, Heatley F, Bradbury A et al.

Scientific Surgery

Laser ablation versus mechanochemical ablation in the treatment of primary varicose veins: A randomized clinical trial. J Vasc Venous 2020; 8: 211-215.

Authors: Tawfik AM, Sorour WA, El-Laboudy ME

Scientific Surgery

Role of compression after radiofrequency ablation of varicose veins: a randomised controlled trial. Eur J Vasc Endovasc Surg 2020; 60: 108-117.

Authors: Onwudike M, Abbas K, McElvenny DM

Scientific Surgery

Apixaban for the treatment of venous thromboembolism associated with cancer. N Engl J Med 2020; 382: 1599-1607

Authors: Agnelli G, Becattini C, Meyer G, Munoz A, Huisman MV, Connors JM et al.

Scientific Surgery

Post-procedural compression vs. no compression after radiofrequency ablation and concomitant foam sclerotherapy of varicose veins: a randomized controlled non-inferiority trial. Eur J Vasc Endovasc Surg 2020; 59: 73-80

Authors: Pihlaja T, Romsi P, Ohtonen P, Jounila J, Pokela M

Scientific Surgery

A randomised controlled trial comparing three different radiofrequency technologies: short-term results of the 3-RF Trial. Eur J Vasc Endovasc Surg 2019; 58: 401-408

Authors: Nyamekye IK, Dattani N, Hayes W, Harding D, Holloway S, Newman J et al.

Scientific Surgery

Five-year outcomes of a randomized trial of treatments for varicose veins. N Engl J Med 2019; 381: 912-922.

Authors: Brittenden J, Cooper D, Dimitrova M, Scotland G, Cotton SC, Elders A et al.

Scientific Surgery

Adjunctive intermittent pneumatic compression for venous thromboprophylaxis. N Engl J Med 2019; 380: 1305-1315.

Authors: Arabi YM, Al-Hameed F, Burns KEA, Mehta S, Alsolamy SJ, Alshahrani MS et al.

Scientific Surgery

A randomized trial of class 2 and class 3 elastic compression in the prevention of recurrence of venous ulceration. J Vacs Surg Venous Lymphat Disord 2018; 6: 717–723.

Authors: Milic DJ, Zivic SS, Bogdanovic DC, Golubovic MD, Lazarevic MV, Lazarevic KK et al.

Scientific Surgery

Twenty-four month results from a randomized trial of cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vas Venous Lymphatic Disorders 2018; 6: 606–613.

Authors: Gibson K, Morrison N, Kolluri R, Vasquez M, Weiss R, Cher D et al.

Scientific Surgery

Extended versus conventional thromboprophylaxis after major abdominal and pelvic surgery: Systematic review and meta-analysis of randomized clinical trials. Surgery 2018; 164: 1234-1240.

Authors: Rausa E, Kelly ME, Asti E, Aiolfi A, Bonitta G, Winter DC et al.

Scientific Surgery

Rivaroxaban for thromboprophylaxis in high-risk ambulatory patients with cancer. N Engl J Med 2019; 380: 720-728.

Authors: Khorana AA, Soff GA, Kakkar AK, Vadhan-Raj S, Riess H, Wun T et al.

Scientific Surgery

Apixaban to prevent venous thromboembolism in patients with cancer. N Engl J Med 2019; 380: 711-719.

Authors: Carrier M, Abou-Nassar K, Mallick R, Tagalakis V, Shivakumar S, Schattner A et al.

Scientific Surgery

A randomized clinical trial of buffered tumescent local anaesthesia during endothermal ablation for superficial venous incompetence. Eur J Vasc Endovasc Surg 2018; 56: 699-708.

Authors: Nandhra S, Wallace T, El-Sheikha J, Leun C, Carradice D, Chetter I et al.

Scientific Surgery

Thromboembolism incidence and prophylaxis use after gastrectomy among Korean patients with gastric adenocarcinoma. The PROTECTOR randomized clinical trial. JAMA Surg 2018; 153: 939-946.

Authors: Jung YJ, Seo HS, Park CH, Jeon HM, Kim J-I, Yim HW et al.

Scientific Surgery

Venous thromboembolism incidence and prophylaxis use after gastrectomy among Korean patients with gastric adenocarcinoma. The PROTECTOR randomized clinical trial. JAMA Surg 2018; 153: 939-946.

Authors: Jung YJ, Seo HS, Park CY, Jeon HM, Kim J-I, Yim HW et al.

Scientific Surgery

Prospective, double-blind, randomized controlled trial comparing electrocoagulation and radiofrequency in the treatment of patients with great saphenous vein insufficiency and lower limb varicose veins. J Vasc Surg Venous Lymphatic 2018; 6: 212-219.

Authors: Beteli CB, Rossi FH, de Almeida BL, Izukawa NM, Rossi CBO, Gabriel SA et al.

Scientific Surgery

Individualised versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome (IDEAL DVT): a multicentre, randomised, single-blind, allocation-concealed, non-inferiority trial. Lancet Haematol 2018; 1: e25-e33.

Authors: Ten Cate-Hoek AJ, Amin EE, Bouman AC, Meijer K, Tick LW, Middeldorp S et al.

Scientific Surgery

Systematic review and meta-analysis of randomized controlled trials evaluating long-term outcomes of endovenous management of lower extremity varicose veins. J Vasc Surg Venous Lymphat Disord 2018; 6: 256-270.

Authors: Kheirelseid EAH, Crowe G, Sehgal R, Liakopoulos D, Bela H, Mulkern E et al.

Scientific Surgery

A randomised clinical trial comparing n-butyl cyanoacrylate, radiofrequency ablation and endovenous laser ablation for the treatment of superficial venous incompetence: two year follow up results. Eur J Vasc Endovasc Surg 2018; 56: 553-560.

Authors: Eroglu E, Alptekin Y

Scientific Surgery

Randomized double-blinded study comparing medical treatment versus iliac vein stenting in chronic venous disease. J Vasc Surg Venous Lymphatic 2018; 6: 183-191.

Authors: Rossi FH, Kambara AM, Izukawa NM, Rodrugues TO, Rossi CB, Sousa AG et al.

Scientific Surgery

A randomized trial of early endovenous ablation in venous ulceration. N Engl J Med 2018; 378: 2105-2114.

Authors: Gohel MS, Heatley F, Liu X, Bradbury A, Bulbulia R, Cullum N et al.

Scientific Surgery

Edoxaban for the treatment of cancer-associated venous thromboembolism. N Engl J Med 2018; 378: 615-624.

Authors: Raskob GE, van Es N, Verhamme P, Carrier M, Di Nisio M, Garcia D et al.

Scientific Surgery

VeClose trial 12-month outcomes of cyanoacrylate closure versus radiofrequency ablation for incompetent great saphenous veins. J Vasc Surg Venous Lymphatic 2017; 5: 321-330.

Authors: Morrison N, Gibson K, Vasquez M, Weiss R, Cher D, Madsen M et al.

Scientific Surgery

Acute effects of graduated elastic compression stockings in patients with symptomatic varicose veins: a randomized double blind placebo controlled trial. Eur J Vasc Endovasc Surg 2018; 55: 118-125.

Authors: Kakkos SK, Timpilis M, Patrinos P, Nikolakopoulos KM, Papageorgopoulou CP, Kouri AK et al.

Scientific Surgery

Low dose aspirin as adjuvant treatment for venous leg ulceration. BMJ 2017: 359: j5157.

Authors: Jull A, Wadham A, Bullen C, Parag V, Kerse N, Waters J et al.

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