Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Effectiveness of intermittent pneumatic compressionin reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial. Lancet 2013; 382: 516-524.

Authors: CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration

Scientific Surgery

Efficacy and safety outcomes of oral anticoagulants and antiplatelet drugs in secondary prevention of venous thromboembolism: systematic review and network meta-analysis. BMJ 2013; 347: f5133.

Authors: Castelluci LA, Cameron C, Le Gal G, Rodger MA, Coyle D, Wells PS et al. et al.

Scientific Surgery

Extended use of dabigatran, warfarin, or placebo in venous thromboembolism. N Engl J Med 2013; 368: 709–718.

Authors: Schulman S, Kearon C, Kakkar AK, Schellong S, Eriksson H, Baanstra D et al. et al.

Scientific Surgery

Apixaban for extended treatment of venous thromboembolism. N Engl J Med 2013; 368: 699–708.

Authors: Agnelli G, Buller HR, Cohen A, Curto M, Gallus AS, Johnson M et al. et al.

Scientific Surgery

A randomized double blind trial of upward progressive versus degressive compressive stockings in patients with moderate to severe chronic venous insufficiency. J Vasc Surg 2012; 56: 1344-1350.

Authors: Couzan S, Leizorovicz A, Laporte S, Mismetti P, Pouget J-F, Chapelle C et al. et al.

Scientific Surgery

Low-dose aspirin for preventing recurrent venous thromboembolism. N Engl J Med 2012; 367: 1979–1987.

Authors: Brighton TA, Eikelboom JW, Mann K, Biostat M, Mister R, Gallus A et al. et al.

Scientific Surgery

Dabigatran, rivaroxaban, or apixaban versus enoxaparin for thromboprophylaxis after total hip or knee replacement: systematic review, meta-analysis, and indirect treatment comparisons. BMJ 2012; 344: e3675.

Authors: Gomez-Outes A, Terleira-Feranadez AI, Suarez-Gea ML, Vargas-Castrillon E

Scientific Surgery

A systematic review and meta-analysis of randomised controlled trials comparing endovenous ablation and surgical intervention in patients with varicose veins. Eur J Vasc Endovasc Surg 2012; 44: 214-223.

Authors: Siribumrungwong B, Noorit P, Wilasrusmee C, Attia J, Thakkinstian A

Scientific Surgery

Aspirin for preventing the recurrence of venous thromboembolism. N Engl J Med 2012; 366: 1959–1967.

Authors: Becattini C, Agnelli G, Schenone A, Elchinger S, Bucherini E, Silingardi M et al. et al.

Scientific Surgery

Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med 2012; 366: 1287–1297.

Authors: The EINSTEIN-PE investigators

Scientific Surgery

Thigh-length versus below-knee compression elastic stockings for prevention of the postthrombotic syndrome in patients with proximal venous thrombosis: a randomized trial. Blood 2012; 119: 1561-1565.

Authors: Prandoni P, Noventa F, Quintavalla R, Bova C, Cosmi B, Siragusa S et al. et al.

Scientific Surgery

Randomized controlled trial to investigate the impact of anticoagulation on the incidence of splenic or portal vein thrombosis after laparoscopic splenectomy. Can J Surg 2011; 54: 227–231.

Authors: Wang H, Kopac D, Brisebois R, Sample C, Shapiro AM

Scientific Surgery

A pilot study on the randomization of inferior vena cava filter placement for venous thromboembolism prophylaxis in high-risk trauma patients. J Trauma 2011: 71: 323–328.

Authors: Rajasekhar A, Lottenberg L, Lottenberg R, Feezor RJ, Armen S, Liu H et al. et al.

Scientific Surgery

Randomized trial of the effect of the low molecular weight heparin nadroparin on survival in patients with cancer. J Clin Oncol 2011; 29: 2071-6.

Authors: van Doormaal FF, Nisio MD, Otten HM, Richel DJ, Prins M, Buller HR. et al.

Scientific Surgery

Therapy of isolated calf muscle vein thrombosis: a randomized controlled study. J Vasc Surg 2010; 52: 1246-1250.

Authors: Schwarz T, Buschmann L, Beyer J, Halbritter K, Rastan A, Schellong S. et al.

Scientific Surgery

Prospective randomized study comparing the clinical outcomes between inferior vena cava Greenfield and TrapEase filters. J Vasc Surg 2010; 52: 394–399.

Authors: Usoh F, Hingorani A, Ascher E, Shiferson A, Patel N, Gopal K et al. et al.

Scientific Surgery

Intermittent pneumatic compression or graduated compression stockings for deep vein thrombosis prophylaxis? A systematic review of direct clinical comparisons. Ann Surg 2010; 251: 393-396.

Authors: Morris RJ, Woodcock JP.

Scientific Surgery

Residual thrombosis on ultrasonography to guide the duration of anticoagulation in patients with deep venous thrombosis: a randomized trial. Ann Intern Med 2009; 150: 577-585.

Authors: Prandoni P, Prins MH, Lensing AW, Ghirarduzzi A, Ageno W, Imberti D et al. et al.

Scientific Surgery

A randomised open-label trial comparing long-term subcutaneous low-molecular-weight heparin compared with oral anticoagulant therapy in the treatment of deep venous thrombosis. Eur J Vasc Endovasc Surg 2009; 37: 349-356.

Authors: Romera A, Cairols MA, Vila-Coll R, Marti X, Colome C, Bonell A et al. et al.

Scientific Surgery

Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009; 361: 2342-2352.

Authors: Schulman S, Kearon C, Kakkar AJ, Mismetti P, Schellong S, Eriksson H et al. et al.

Scientific Surgery

Catheter-directed thrombolysis vs. anticoagulant therapy alone in deep vein thrombosis: results of an open randomized controlled trial reporting on short term patency. J Thromb Haemost 2009; 7: 1268-1275.

Authors: Enden T, Klow NE, Sandvik L, Slagsvold CE, Ghanima W, Hafsahl G et al. et al.

Scientific Surgery

Warfarin thromboprophylaxis in cancer patients with central venous catheters (WARP): an open label randomised trial. Lancet 2009; 373: 567-574.

Authors: Young AM, Billingham LJ, Begum G, Kerr DJ, Hughes AI, Rea DW et al. et al.

Scientific Surgery

Fluvastatin and perioperative events in patients undergoing vascular surgery. N Engl J Med 2009; 361: 980-989.

Authors: Schouten O, Boersma E, Hoeks SE, Benner R, van Urk H, van Sambeek MRHM et al. et al.

Scientific Surgery

Serial 2-point ultrasonography plus D-dimer vs. whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis JAMA 2008; 300: 1653-1659

Authors: Bernardi E, Camporese G, Buller HR, Siragusa S, Imberti D, Berchio A et al et al.

Scientific Surgery

Effect of prolonged treatment with compressions stockings to prevent post-thrombotic sequelae: a randomised controlled trial J Vasc Surg 2008; 47: 1015-1021.

Authors: Aschwanden M, Jeanneret C, Koller MT, Thalhammer C, Bucher HC, Jaeger KA. et al.

Scientific Surgery

A factorial randomized trial of pentoxifylline or placebo, four-layer or single-layer compression and knitted viscose or hydrocolloid dressings for venous ulcers. J Vasc Surg 2007; 48: 134-141.

Authors: Nelson EA, Prescott RJ, Harper DR, Gibson B, Brown D, Ruckley CV. et al.

Scientific Surgery

Computed tomographic pulmonary angiography vs. ventilation-perfusion lung scanning in patients with suspected pulmonary embolism. A randomised controlled trial. JAMA 2007; 298: 2743¿2753.

Authors: Anderson DR, Kahn SR, Rodger MA, Kovacs MJ, Morris T, Hirsch A et al.

Scientific Surgery

Heart Outcomes Prevention Evaluation 2 (HOPE-2) Investigators. Homocysteine-lowering therapy and risk for venous thromboembolism: a randomized trial. Ann Intern Med 2007; 146: 761-767.

Authors: Ray JG, Kearon C, Yi Q, Sheridan P, Lonn E.

Scientific Surgery

Anticoagulation for three versus six months in patients with deep vein thrombosis or pulmonary embolism, or both: randomised trial. BMJ 2007; 334: 674-677.

Authors: Campbell IA, Bentley DP, Prescott RJ, Routledge PA, Shetty HGM, Williamson IJ. et al.

Scientific Surgery

Idraparinux versus standard therapy for venous thromboembolic disease. N Engl J Med 2007; 357: 1094-1104.

Authors: The van Gogh Investigators.

Older Entries

Newer Entries