Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Emergency surgery in acute diverticulitis: a systematic review. Dis Colon Rectum 2020; 63: 397-405.

Authors: Beyer-Berjot L, Maggiori L, Loiseau D, Korwin J-D, Bongiovanni J-P, Lesprit P et al.

Scientific Surgery

Prophylactic intra-abdominal drainage following colorectal anastomoses. A systematic review and meta-analysis of randomized controlled trials. Am J Surg 2020; 219: 164-174.

Authors: Podda M, Di Saverio S, Davies JR, Atzeni J, Balestra F, Virdis F et al.

Scientific Surgery

Cancer prevention with aspirin in hereditary colorectal cancer (Lynch Syndrome), a 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double blind, randomised, placebo-controlled trial. Lancet 2020; 395: 1855-1863.

Authors: Burn J, Sheth H, Elliott F, Reed L, Macrae F, Mecklin J-P et al.

Scientific Surgery

Modifiable pathways for colorectal cancer: a mendelian randomisation analysis. Lancet Gastroenterol Hepatol 2020; 5: 142-151

Authors: Cornish AJ, Law PJ, Tomofeeva M, Palin K, Farrington SM, Palles C et al.

Scientific Surgery

Simple versus complex preoperative carbohydrate drink to preserve perioperative insulin sensitivity in laparoscopic colectomy. A randomized controlled trial. Ann Surg 2020; 271: 819-826

Authors: Karimian N, Kaneva P, Donatelli F, Stein B, Liberman AS, Charlebois P et al.

Scientific Surgery

Transversus abdominis plane block in laparoscopic colorectal surgery: a systematic review. Dis Colon Rectum 2019; 62: 1248-1255

Authors: Wu RC, Jensen CC, Douaiher J, Madoff RD, Kwaan MR

Scientific Surgery

Perioperative FOLFOX 4 versus FOLFOX 4 plus Cetuximab versus immediate surgery for high-risk stage II and III colon cancers. A phase II multicenter randomized controlled trial (PRODIGE 22). Ann Surg 2020; 271: 637-645

Authors: Karoui M, Rullier A, Piessen G, Legoux JL, Barbier E, De Chaisemartin C et al.

Scientific Surgery

Comparison of bowel cleansing efficacy, safety, bowel movement kinetics, and patient tolerability of same-day and split-dose bowel preparation using 4 L of polyethylene glycol: a prospective randomized study. Dis Colon Rectum 2019; 62: 1518-1527

Authors: Seo M, Gweon T-G, Huh CW, Ji JS, Choi H

Scientific Surgery

Early versus standard closure of temporary ileostomy in patients with rectal cancer: a randomized controlled trial. J Surg Oncol 2019; 120: 249-299

Authors: Kuliavas J, Dulskas A, Kryzauskas M, Pauza K, Kilius A, Rudinskaite G et al.

Scientific Surgery

Short-term outcomes of transanal hemorrhoidal dearterialization with mucopexy versus vessel-sealing device hemorrhoidectomy for grade III to IV hemorrhoids: a prospective randomized multicenter trial. Dis Colon Rectum 2019; 62: 988-996

Authors: Trenti L, Biondo S, Kreisler Moreno E, Sanchez-Garcia JL, Espin-Basany E, Landaluce-Olavarria A et al.

Scientific Surgery

Drainage Seton versus external anal sphincter-sparing Seton after rerouting of the fistula tract in the treatment of complex anal fistula: a randomized controlled trial. Dis Colon Rectum 2019; 62: 980-987

Authors: Omar W, Alqasaby A, Abdelnaby M, Youssef M, Shalaby M, Anwar Abdel-Razik M et al.

Scientific Surgery

Quality of life after curative resection for rectal cancer in patients treated with adjuvant chemotherapy compared with observation: results of the randomized phase III SCRIPT Trial. Dis Colon Rectum 2019; 62: 711-720

Authors: van der Valk MJ, Hilling DE, Meershoek-Klein Kranenbarg E, Peeters K, Kapiteijn E, Tsonaka R et al.

Scientific Surgery

Colorectal cancer screening with faecal testing, sigmoidoscopy or colonoscopy: a systematic review and network meta-analysis. BMJ Open 2019; 9: e032773

Authors: Jodal HC, Helsingen LM, Anderson JC, Lytvyn L, Vandvik PO, Emilsson L et al.

Scientific Surgery

Intracorporeal or extracorporeal ileocolic anastomosis after laparoscopic right colectomy. A double-blinded randomized controlled trial. Ann Surg 2019; 270: 762-767.

Authors: Allaix M, Degiuli M, Bonino MA, Arezzo A, Mistrangelo M, Passera R et al.

Scientific Surgery

Does a longer waiting period after neoadjuvant radio-chemotherapy improve the oncological prognosis of rectal cancer? Three years’ follow-up results of the Greccar-6 randomized multicenter trial. Ann Surg 2019; 270: 747-754

Authors: Lefèvre J, Mineur L, Cachanado M, Denost Q, Rouanet P, de Chaisemartin C et al.

Scientific Surgery

Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicenter, open-label, randomized trial. Lancet Gastroenterol Hepatol 2019; 4: 761-770

Authors: Klaver CEL, Wisselink DD , Punt CJA , Snaebjornsson P , Crezee J, Aalbers AG et al.

Scientific Surgery

Hartmann’s procedure versus sigmoidectomy with primary anastomosis for sigmoid diverticulitis with purulent or faecal peritonitis (LADIES): a multicenter, parallel-group, open label superiority trial. Lancet Gastroenterol Hepatol 2019; 4: 599-610

Authors: Lambrichts DPV, Vennix S , Musters GD , Mulder IM , Swank HA , Hoofwijk AGM et al.

Scientific Surgery

Mechanical and oral antibiotic bowel preparation versus no bowel preparation for elective colectomy (MOBILE): a multicentre, randomised, parallel, single-blinded trial. Lancet 2019; 394: 840-848.

Authors: Koskenvuo L, Lehtonen T, Koskensalo S, Rasilainen S, Klintrup K, Ehrlich A et al.

Scientific Surgery

Purse-string approximation vs. primary closure with a drain for stoma reversal surgery: results of a randomized clinical trial. Surgery Today 2019; 49: 231–237.

Authors: Amamo K, Ishida H, Kumamoto K, Okada N, Hatano S, Chika N et al.

Scientific Surgery

Low ligation of inferior mesenteric artery in laparoscopic anterior resection for rectal cancer reduces genitourinary dysfunction. Results from a randomized controlled trial (HIGHLOW Trial). Ann Surg 2019; 269: 1018-1024.

Authors: Mari G, Crippa J, Cocozza E, Berselli M, Livraghi L, Carzaniga P et al.

Scientific Surgery

Laparoscopic versus open resection for rectal cancer. A non-inferiority meta-analysis of quality of surgical resection outcomes. Ann Surg 2019; 269: 849-855.

Authors: Acuna SA, Chesney TR, Ramjist JK, Shah PS, Kennedy ED, Naxter NN et al.

Scientific Surgery

Clinical outcome after rectal replacement with side-to-end, colon-J-pouch, or straight colorectal anastomosis following total mesorectal excision. A Swiss Prospective, Randomized, Multicenter Trial (SAKK 40/04). Ann Surg 2019; 269: 827-835.

Authors: Marti W, Curti G, Wehrli H, Grieder F, Graf M, Gloor B et al.

Scientific Surgery

Better function with a colonic J-pouch or a side-to-end anastomosis? A randomized controlled trial to compare the complications, functional outcome, and quality of life in patients with low rectal cancer after a J-pouch or a side-to-end anastomosis. Ann Surg 2019; 269: 815-826.

Authors: Parc Y, Ruppert R, Fuerst A, Golcher H, Zutshi M, Hull T et al.

Scientific Surgery

Effect of a single aspirin dose prior to fecal immunochemical testing on test sensitivity for detecting advanced colorectal neoplasms. A randomized clinical trial. JAMA 2019; 321: 1686-1692.

Authors: Brenner H, Calderazzo S, Seufferlein T, Ludwig L, Dikopoulos N, Mangold J et al.

Scientific Surgery

Long-term outcome of surgery versus conservative management for recurrent and ongoing complaints after an episode of diverticulitis. 5-year follow-up results of a multicenter randomized controlled trial (DIRECT-Trial). Ann Surg 2019; 269: 612-620.

Authors: Bolkenstein HE, Consten ECJ, van der Palen J, van de Wall BJ, Broeders IA, Bemelman WA et al.

Scientific Surgery

Disease-free survival and local recurrence after laparoscopic-assisted resection or open resection for rectal cancer. The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial. Ann Surg 2019; 269: 596-602.

Authors: Stevenson ARL, Solomon M, Brown CSB, Lumley JW, Hewett P, Clouston A et al.

Scientific Surgery

Disease-free survival and local recurrence for laparoscopic resection compared with open resection of stage II to III rectal cancer. Follow-up results of the ACOSOG Z6051 randomized controlled trial. Ann Surg 2019; 269: 589-595.

Authors: Fleshman J, Branda ME, Sargent DJ, Boller AM, George VV, Abbas MA et al.

Scientific Surgery

Intraperitoneal local anesthetic instillation and postoperative infusion improves functional recovery following colectomy. A randomized controlled trial. Dis Colon Rectum 2018; 61: 1205-1216.

Authors: Duffield JA, Thomas ML, Moore JW, Hunter RA, Wood C, Gentili S et al.

Scientific Surgery

Operative strategies for perforated diverticulitis. A systematic review and meta-analysis. Dis Colon Rectum 2018; 61: 1442-1453.

Authors: Acuna SA, Wood T, Chesney TR, Dossa F, Wexner SDS, Quereshy F et al.

Scientific Surgery

Use of prophylactic mesh when creating a colostomy does not prevent parastomal hernia. A randomized controlled trial—STOMAMESH. Ann Surgery 2019; 269: 427-431.

Authors: Odensten C, Strigård K, Rutegård J, Dahlberg M, Ståhle U, Gunnarsson U et al.

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