Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs). EJSO 2017; 43: 1550-1558.

Authors: Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Nowak K, Kieser M et al.

Scientific Surgery

Circular stapling versus triangulating stapling for the cervical esophagogastric anastomosis after esophagectomy in patients with thoracic esophageal cancer: A prospective, randomized, controlled trial. Surgery 2017; 162: 131-138.

Authors: Hayata K, Nakamori M, Nakamura M, Ojima T, Iwahashi M, Katsuda M et al.

Scientific Surgery

A randomised trial of endoscopic submucosal dissection versus endoscopic mucosal resection for early Barrett’s neoplasia. Gut 2017; 66: 783-793.

Authors: Terheggen G, Horn EM, Vieth M, Gabbert H, Enderle M, Neugebauer A et al.

Scientific Surgery

Does prolonged enteral feeding with supplemental omega-3 fatty acids impact on recovery post-esophagectomy: results of a randomized double-blind trial. Ann Surg 2017; 266: 720-728.

Authors: Healy LA, Ryan A, Doyle S, Ní Bhuachalla EB, Cushen S, Segurado R et al.

Scientific Surgery

Minimally invasive versus open esophageal resection: three-year follow-up of the previously reported randomized controlled trial: The TIME Trial. Ann Surg 2017; 266: 232-236.

Authors: Straatman J, van der Wielen N, Cuesta MA, Daams F, Roig Garcia J, Bonavina L et al.

Scientific Surgery

Seventeen-year outcome of a randomized clinical trial comparing laparoscopic and conventional Nissen fundoplication: a plea for patient counseling and clarification. Ann Surg 2017; 266: 23-28.

Authors: Oor J, Roks D, Broeders J, Hazebroek E, Gooszen H

Scientific Surgery

Survival after neoadjuvant and adjuvant treatments compared to surgery alone for resectable esophageal carcinoma: a network meta-analysis. Ann Surg 2017; 265: 481-491.

Authors: Pasquali S, Yim G, Vohra R , Mocellin S, Nyanhongo D, Marriott P et al.

Scientific Surgery

Peri-operative chemotherapy with or without bevacizumab in operable oesophagogastric adenocarcinoma (UK Medical Research Council ST03): primary analysis results of a multicentre, open-label, randomised phase 2-3 trial. Lancet Oncol 2017; 18: 357-370.

Authors: Cunningham D, Stenning SP , Smyth EC, Okines AF, Allum WH, Rowley S et al.

Scientific Surgery

Long-term results of the European achalasia trial: a multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy. Gut 2016; 65: 732-739.

Authors: Moonen A, Annese V, Belmans A, Bredenoord AJ, des Varannes SB, Costantini M et al.

Scientific Surgery

Laparoscopic mesh-augmented hiatoplasty with cardiophrenicopexy versus laparoscopic Nissen fundoplication for the treatment of gastroesophageal reflux disease: a double-center randomized controlled trial. Ann Surg 2015; 262: 721–727.

Authors: Müller-Stich B, Linke G, Senft J, Achtstätter V, Müller P, Diener M et al. et al.

Scientific Surgery

Randomized controlled study to evaluate the efficacy of a preoperative respiratory rehabilitation program to prevent postoperative pulmonary complications after esophagectomy. Dig Surg 2015; 32: 331-337.

Authors: Yamana I, Takeno S, Hashimoto T, Maki K, Shibata R, Shiwaku H et al. et al.

Scientific Surgery

Comparative study between laparoscopic Heller Myotomy versus pneumatic dilatation for treatment of early achalasia: a prospective randomized study. J Lap Adv Surg Tech A 2015, 25: 460-464.

Authors: Hamdy E, El Nakeeb A, El Hanfy E, El Hemaly M, Salah T, Hamed H et al. et al.

Scientific Surgery

Surgery alone versus chemoradiotherapy followed by surgery for stage I and II esophageal cancer: final analysis of randomized controlled phase III trial FFCD 9901. J Clin Oncol 2014; 32: 2416-2422.

Authors: Mariette C, Dahan L, Mornex F, Maillard E, Thomas P-A, Meunier B et al. et al.

Scientific Surgery

Robotic Nissen fundoplication for gastroesophageal reflux disease: a meta-analysis of prospective randomized controlled trials. Surg Today 2014; 44: 1415-1423.

Authors: Yao G, Liu K, Fan Y

Scientific Surgery

Radiofrequency ablation vs. endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia. A randomized clinical trial. JAMA 2014; 311: 1209-1217.

Authors: Phao KN, van Vilsteren FGI, Weusten BLAM, Bisschops R, Schoon EJ, Ragunath K et al. et al.

Scientific Surgery

A randomized controlled trial comparing antioxidant-enriched enteral nutrition with immune-enhancing enteral nutrition after esophagectomy for cancer. Surg Today 2013; 43: 1240-1249.

Authors: Nagano T, Fujita H, Tanaka T, Matono S, Murata K, Ishibashi N et al. et al.

Scientific Surgery

Efficacy and safety of lesogaberan in gastro-oesophageal reflux disease: a randomised controlled trial. Gut 2013; 62: 1248–1255.

Authors: Shaheen NJ, Denison H, Bjorck K, Karlsson M, Silberg DG

Scientific Surgery

A prospective randomized controlled trial of semi-mechanical versus hand-sewn or circular stapled esophagogastrostomy for prevention of anastomotic stricture. World J Surg 2013; 37: 1043-1050.

Authors: Wang WP, Gao Q, Wang KN, Shi H, Chen LQ

Scientific Surgery

Laparoscopic anterior 180-degree versus Nissen fundoplication for gastroesophageal reflux disease: systematic review and meta-analysis of randomized clinical trials. Ann Surg 2013; 257: 850-859.

Authors: Broeders J, Roks DJ, Ahmed AU, Watson DI, Baigrie RJ, ZhanGuo C et al. et al.

Scientific Surgery

Effect of short-term versus prolonged nasogastric decompression on major post-esophagectomy complications. A parallel-group, randomized trial. Arch Surg 2012; 147: 747-751.

Authors: Misty RC, Vijayabhaskar R, Karimundackal G, Jiwnani S, Pramesh CS

Scientific Surgery

Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX). BMJ 2013; 346: f1908.

Authors: Grant AM, Cotton SC, Boachie C, Ramsay CR, Krukowski ZH, Heading RC et al. et al.

Scientific Surgery

Hand-sewn versus mechanical esophagogastric anastomosis after esophagectomy: a systematic review and meta-analysis. Ann Surg 2013; 257: 238–248.

Authors: Honda M, Kuriyama A, Noma H, Nunobe S, Furukawa T

Scientific Surgery

Impact of perioperative administration of synbiotics in patients with esophageal cancer undergoing esophagectomy: a prospective randomized controlled trial. Surgery 2012; 152: 832–842.

Authors: Tanaka K, Yano M, Motoori M, Kishi K, Miyashiro I, Ohue M et al. et al.

Scientific Surgery

Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med 2012; 366: 2074-2084.

Authors: Van Hagen P, Hulsof MCCM, van Lanschot JJB, Steyerberg EW, Henegouwen MIBV, Wijnhoven BPL et al. et al.

Scientific Surgery

Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial. Lancet 2012; 379: 1887-1892.

Authors: Biere SS, Henegouwen MIVB, Maas KW, Bonavina L, Rosman C, Garcia JR et al. et al.

Scientific Surgery

Meta-analysis of robot-assisted versus conventional laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease. ANZ J Surg 2012; 82: 112-117.

Authors: Wang Z, Zheng Q, Jin Z

Scientific Surgery

Five-year outcome after laparoscopic anterior partial versus Nissen fundoplication: four randomized trials. Ann Surg 2012; 255: 637–642.

Authors: Broeders JA, Roks DJ, Jamieson GG, Devitt PG, Baigrie RJ, Watson DI et al.

Scientific Surgery

Five-year outcomes of a randomized phase III trial comparing adjuvant chemotherapy with S-1 versus surgery alone in stage II or III gastric cancer. J Clin Oncol 2011; 29: 4387–4393.

Authors: Sasako M, Sakuramoto S, Katai H, Kinoshita T, Furukawa H, Yamaguchi T et al. et al.

Scientific Surgery

Biologic prosthesis to prevent recurrence after laparoscopic paraesophageal hernia repair: long-term follow-up from a multicenter, prospective, randomised trial. J Am Coll Surg 2011; 213: 461-468.

Authors: Oelschlager BK, Pellegrini CA, Hunter JG, Brunt ML, Soper NJ, Sheppard BC et al.

Scientific Surgery

End-to-end versus end-to-side esophagogastrostomy after esophageal cancer resection: a prospective randomized study. Ann Surg 2011; 254: 226-233.

Authors: Nederlof N, Tilanus H, Tran TCK, Hop WCJ, Wijnhoven B, de Jonge J. et al.

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