This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A double-blind randomized controlled trial of toremifen therapy for mastalgia. Arch Surg 2006; 141: 43-47.

Published: 1st January 2006

Authors: Gong C, Song E, Jia W, Qin L, Guo J, Jia H et al. et al.

Conclusion

Of 104 women who received toremifen 30mg daily, 72 (69 per cent) responded with a reduction in breast pain, compared to 29/91 ( 32 per cent) controls, P<0.001. The effect was better for cyclical mastalgia.

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