This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A polymer-coated, paclitaxel eluting stent (Eluvia) versus a polymer-free, paclitaxel-coated stent (Zilver PTX) for endovascular femoropopliteal intervention (IMPERIAL): a randomized non-inferiority trial. Lancet 2018; 392: 1541-1551.

Published: 19th December 2018

Authors: Gray WA, Keirse K, Soga Y, Benko A, Babaev A, Yokoi Y et al.

Conclusion

Two different drug-eluting stents were compared in 465 patients with intermittent claudication due to superficial femoral or proximal popliteal artery disease. At twelve months, patency rates were similar for polymer-coated (86.8 per cent) and polymer-free stents (91 per cent). Adverse event rates and secondary revascularization procedures were similar.

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Effect of low-intensity vs high-intensity home-based walking exercise on walk distance in patients with peripheral artery disease. The LITE Randomized Clinical Trial. JAMA 2021; 325: 1266-1276.

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Randomized controlled trial of vacuum therapy for intermittent claudication. J Vasc Surg 2020; 71: 1692-1701.

Authors: Hageman D, Fokkenrood HJP, van Deursen BAC, Gommans LNM, Cancrinus E, Scheltinga MRM et al.

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Randomized controlled trial of vacuum therapy for intermittent claudication. J Vasc Surg 2020; 71: 1692-1701

Authors: Hageman D, Fokkenrood HJP, van Deursen BAC, Gommans LNM, Cancrinus E, Scheltinga MRM et al.

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The effect of supervised exercise, home based exercise and endovascular revascularisation on physical activity in patients with intermittent claudication: a network meta-analysis. Eur J Vasc Endovasc Surg 2019; 58: 383-392

Authors: Van den Houten MML , Hageman D , Gommans LNM, Kleijnen J , Scheltinga MRM , Teijink JAP et al.

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Wearable sensor technology efficacy in peripheral vascular disease (wSTEP). A randomized controlled trial. Ann Surg 2018; 268: 1113-1118.

Authors: Normahani P, Kwasnicki R, Bicknell C, Allen L, Jenkins MP, Gibbs R et al.

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Systematic review and meta-analysis of clinical trials examining the benefit of exercise programmes using Nordic Walking in patients with peripheral artery disease. Eur J Vasc Endovasc Surg 2018; 56: 534–543.

Authors: Golledge J, Maarij K, Moxon JV, Beard JD, Girold S, Wrang H et al.

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Systematic review and meta-analysis of high-pressure intermittent limb compression for the treatment of intermittent claudication. J Vasc Surg 2018; 67: 620–628.e2.

Authors: Oresanya L, Mazzei M, Bashir R, Farooqui A, Athappan G, Roth S et al.

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A feasibility double-blind randomized placebo-controlled trial of extracorporeal shockwave therapy as a novel treatment for intermittent claudication. J Vasc Surg 2018; 67: 514–521.e2.

Authors: Harwood AE, Green J, Cayton T, Raza A, Wallace T, Carradice D et al.

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A systematic review of treatment of intermittent claudication in the lower extremities. J Vasc Surg 2015; 61: Suppl 54S–73S.

Authors: Malgor RD, Alalahdab F, Elraiyah TA, Rizvi AZ, Lane M, Prokop LJ et al. et al.