The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A prospective, randomized phase II study of adjuvant gemcitabine versus S-1 after major hepatectomy for biliary tract cancer (KHBO 1208). Ann Surg 2019; 270: 230-237.

Published: 12th November 2019

Authors: Kobayashi S, Nagano H, Tomokuni A, Gotoh K, Sakai D, Hatano E et al.

Conclusion

In this study that included 70 patients, adjuvant chemotherapy with S-1 improved 1-year recurrence-free survival (62.9 versus 51.4 per cent) and overall survival (97.1 versus 80 per cent) compared to standard chemotherapy.

Pubmed Link