This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A randomized controlled pilot trial of modified whole blood versus component therapy in severely injured patients requiring large volume transfusions. Ann Surg 2013; 285: 527–533.

Published: 18th February 2014

Authors: Cotton BA, Podbielski J, Camp E, Welch T, del Junco D, Bai Y et al. et al.

Conclusion

The use of whole blood did not reduce the overall rate of 24h transfusion volume in this study of 107 patients. If patients with severe brain injury were excluded, however, patients resuscitated with whole blood needed fewer red blood cells, platelets and total products.

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Open preperitoneal inguinal hernia repair, TREPP versus TIPP in a randomized clinical trial. Ann Surg 2021; 274: 698-704.

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Central venous access devices for the delivery of systemic anticancer therapy (CAVA): a randomised controlled trial. Lancet 2021; 398: 403-415.

Authors: Moss JG, Wo O, Bodenham AR, Agarwal R, Menne TF, Jones BL et al.

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Randomized controlled study investigating the effect of a dedicated in-house art gallery on the recovery of patients after major oncologic surgery. Ann Surg 2021; 274: 264-270.

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