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A randomized, double‐blind, placebo‐controlled trial of probiotics to reduce the severity of oral mucositis induced by chemoradiotherapy for patients with nasopharyngeal carcinoma. Cancer 2019; 125: 1081-1090

Published: 5th March 2020

Authors: Jiang C, Wang H, Xia C, Dong Q, Chen E, Qiu Y et al.


Some 99 patients were randomized 2:1. The rate of severe oral mucositis was reduced from 45.7 to 15.5 per cent, P<0.05. The probiotics significantly enhanced measures of immune system function, and maintained intestinal microbial diversity.

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