The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A randomized, prospective trial of operative treatments for hyperparathyroidism in patients with multiple endocrine neoplasia type 1. Surgery 2014; 156: 1326-1335.

Published: 24th February 2015

Authors: Lairmore TC, Govednik CM, Quinn CE, Sigmond BR, Lee CY, Jupiter DC et al.

Conclusion

Thirty-two patients were randomly allocated to subtotal parathyroidectomy (SP) or total parathyroidectomy with autotransplantation (TP/AT). Rates of recurrent hyperparathyroidism (SP 24 per cent, TP/AT 13 per cent) and permanent hypoparathyroidism (12 vs. 7 per cent, respectively) were similar. Patients who had SP avoided obligatory postoperative hypoparathyroidism.

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