This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
A systematic review of the efficacy of aspirin monotherapy versus other antiplatelet therapy regimens in peripheral arterial disease. J Vasc Surg 2018; 67: 1922-1932.
Published: 15th October 2018
Authors: Beiswenger AC, Jo A, Harth K, Kumins NH, Shishehbor MH, Kashyap VS et al.
Conclusion
Fourteen studies (ten RCTs) looked at the effect of dual antiplatelets after revascularisation procedures. The duration of use was variable, but combination treatment reduced major cardiovascular events (P<).0001) and improved results of the procedure. Rates of major bleeding were similar.
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