This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Adjuvant chemotherapy in resected bile duct cancer: A systematic review and meta-analysis of randomized trials. Crit Rev Oncol Hematol 2019; 143: 124-129
Published: 22nd November 2019
Authors: Messina C , Merz V , Frisinghelli M , Trentin C , Grego E , Veccia A et al.
Conclusion
Adjuvant chemotherapy improved recurrence-free survival (hazard ratio 0.83, 95 per cent confidence interval 0.69 to 0.99), but not overall survival (0.84, 0.65 to 1.08). Subgroup analysis gave similar results for patients with positive lymph nodes, and an involved resection margin.
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