The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Adjuvant chemotherapy with gemcitabine and long term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial. JAMA 2013; 310: 1473-1481.

Published: 14th April 2014

Authors: Oettle H, Neuhaus P, Hochhaus A, Hartmann JT, Gellert K, Ridwelski K et al. et al.

Conclusion

This study included 368 patients followed for a median of 136 months. Adjuvant gemcitabine for six months improved median disease-free survival (13.4 versus 6.7 months, P<0.001) and overall 5-year survival: 20.7 versus 10.4 per cent, P=0.01.

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