The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Adjuvant pembrolizumab versus placebo in resected stage III melanoma. N Engl J Med 2018; 378: 1789-1801.

Published: 9th August 2018

Authors: Eggermont AMM, Blank CU, Mandala M, Long GV, Atkinson V, Dalle S et al.

Conclusion

Active treatment continued for one year in this study that included 1019 patients. One year recurrence-free survival improved from 61 to 75.4 per cent, hazard ratio for recurrence or death 0.57, 95 per cent confidence interval 0.43 to 0.74; P<0.001.

Pubmed Link