This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Antibiotic irrigation during pancreatoduodenectomy to prevent infection and pancreatic fistula: a randomized controlled clinical trial. Surgery 2019; 166: 469-475

Published: 5th March 2020

Authors: Maatman TK, Weber DJ, Timsina LR, Zyromski NJ, Koniaris LG, House MG et al.

Conclusion

Clinically relevant pancreatic fistula occurred in 12 per cent after antibiotic irrigation and 11 per cent in controls. Neither did antibiotic irrigation reduce overall surgical site infection: 11 versus 15 per cent, respectively.

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