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Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children. A systematic review and meta-analysis. Ann Surg 2019; 270: 1028-1040

Published: 24th January 2020

Authors: Podda M, Gerardi C, Cillara N, Fearnhead N, Gomes CA, Birindelli A et al.


There were 20 studies including 3618 patients. Surgical treatment was associated with higher rate of complication-free successful treatment (82.3 versus 67.2 per cent, P<0.0001) and treatment efficacy after one year (93.1 versus 72.6 per cent, P<0.00001).

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