This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Antibiotics versus surgical therapy for uncomplicated appendicitis: systematic review and meta-analysis of controlled trials (PROSPERO 2015: CRD42015016882). Ann Surg 2017; 265: 889-900.

Published: 14th June 2017

Authors: Harnoss J, Zelienka I, Probst P, Grummich K, Müller-Lantzsch C, Harnoss J et al.

Conclusion

Four RCTs and four cohort studies were included (2551 patients). Some 26.5 per cent of patients treated conservatively needed appendicectomy within a year. Adverse events and duration of hospital stay were longer in the antibiotic group.

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