This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Apixaban to prevent venous thromboembolism in patients with cancer. N Engl J Med 2019; 380: 711-719.

Published: 29th April 2019

Authors: Carrier M, Abou-Nassar K, Mallick R, Tagalakis V, Shivakumar S, Schattner A et al.

Conclusion

Patients starting chemotherapy who were at intermediate or high risk of venous thromboembolism (VTE) were included. Apixaban reduced the VTE rate from 10.2 to 4.2 per cent (P<0.001) in this study of 563 patients.

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