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Association of autofluorescence-based detection of the parathyroid glands during total thyroidectomy with postoperative hypocalcemia risk. Results of the PARAFLUO multicenter randomized clinical trial. JAMA Surg 2020; 155: 106-112

Published: 15th June 2020

Authors: Benmiloud F, Godiris-Petit G, Gras R, Gillot J-C, Turrin N, Penaranda G et al.


The additional use of near-infrared autofluorescence light to identify parathyroid glands during total thyroidectomy in this study that included 245 procedures reduced the rate of temporary postoperative hypocalcaemia from 21.7 to 9.1 per cent (P=0.007). Permanent hypocalcaemia rates were similar: none versus 1 .6 per cent, respectively).

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