This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Biological mesh closure of the pelvic floor after extralevator abdominoperineal resection for rectal cancer; a multicenter randomized controlled trial (the BIOPEX study). Ann Surg 2017; 265: 1074-1081.

Published: 28th November 2017

Authors: Musters G, Klaver CE, Bosker RJI, Burger JWA, van Duijvendijk P, van Etten B et al.

Conclusion

In this study that included 104 procedures, perineal healing was not affected by mesh implantation (uncomplicated healing at 30 days 66 per cent with sutures and 63 per cent with mesh). After one year mesh reduced the rate of perineal hernia from 27 to 13 per cent, P=0.0316.

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Low ligation of inferior mesenteric artery in laparoscopic anterior resection for rectal cancer reduces genitourinary dysfunction. Results from a randomized controlled trial (HIGHLOW Trial). Ann Surg 2019; 269: 1018-1024.

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Laparoscopic versus open resection for rectal cancer. A non-inferiority meta-analysis of quality of surgical resection outcomes. Ann Surg 2019; 269: 849-855.

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Robotic versus laparoscopic minimally invasive surgery for rectal cancer: a systematic review and meta-analysis of randomized controlled trials. Ann Surg 2018; 267: 1034-1046.

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