This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Biological mesh closure of the pelvic floor after extralevator abdominoperineal resection for rectal cancer: a multicenter randomized controlled trial (the BIOPEX-study). Ann Surg 2017; 265: 1074-1081.

Published: 30th September 2017

Authors: Musters G, Klaver CEL, Bosker R, Burger J, van Duijvendijk P, van Etten B et al.

Conclusion

The use of biological mesh to repair the pelvic floor did not improve the rate of uncomplicated healing at 30 days compared to primary closure (63 versus 66 per cent) but did reduce the rate of perineal hernia at one year (13 versus 27 per cent, P=0.03).

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