This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Botulinum toxin versus pneumatic dilatation in the treatment of achalasia: a randomised trial. Gut 1999; 44: 231-9.

Published: 1st January 1999

Authors: Vaezi MF, Richter JE, Wilcox CM, Schroeder PL, Birgisson S, Slaughter RL et al. et al.

Conclusion

Pneumatic dilatation was more effective up to one year in this study of 42 patients. Dilatation had a higher cumulative remission rate and an improvement in objective parameters

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IMPPACT (Intravenous Monotherapy for Postoperative Perforated Appendicitis in Children Trial). Randomized clinical trial of monotherapy versus multi-drug antibiotic therapy. Ann Surg 2021; 274: 406-410.

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A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

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