This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Capecitabine plus oxaliplatin compared with fluorouracil/folinic acid as adjuvant therapy for stage III colon cancer: final results of the NO16968 randomized controlled phase III trial. J Clin Oncol 2015; 33: 3733-3740.
Published: 29th March 2016
Authors: Schmoll H-J, Tabernero J, Maroun J, de Braud F, Price T, Van Cutsem E et al. et al.
Conclusion
In this study that included 1886 patients, capecitabine/oxaliplatin improved disease-free survival after seven years (hazard ratio 0.8, 95 per cent confidence interval 0.69 to 0.93, P=0.004) and overall survival: 73 versus 67 per cent, P=0.04.
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