The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Central venous access devices for the delivery of systemic anticancer therapy (CAVA): a randomised controlled trial. Lancet 2021; 398: 403-415.

Published: 9th December 2021

Authors: Moss JG, Wo O, Bodenham AR, Agarwal R, Menne TF, Jones BL et al.


Three implantable devices for intravenous therapy were compared in this study that included 1061 patients. Totally implanted ports were shown to be safer than Hickman and PICC lines, with fewer complications.

Pubmed Link