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Combined surgery and extensive intraoperative peritoneal lavage vs surgery alone for treatment of locally advanced gastric cancer. The SEIPLUS randomized clinical trial. JAMA Surg 2019; 154: 610-616

Published: 23rd December 2019

Authors: Guo J, Xu A, Sun X, Zhao X, Xia Y, Rao H et al.


Some 550 patients having gastrectomy for gastric cancer were included. The addition of extensive intraoperative lavage reduced the mortality rate (none versus 1.9 per cent, P=0.02) and perioperative complication rates (11.1 versus 17 per cent, P=0.04).

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