The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Combined surgery and extensive intraoperative peritoneal lavage vs surgery alone for treatment of locally advanced gastric cancer. The SEIPLUS randomized clinical trial. JAMA Surg 2019; 154: 610-616

Published: 23rd December 2019

Authors: Guo J, Xu A, Sun X, Zhao X, Xia Y, Rao H et al.


Some 550 patients having gastrectomy for gastric cancer were included. The addition of extensive intraoperative lavage reduced the mortality rate (none versus 1.9 per cent, P=0.02) and perioperative complication rates (11.1 versus 17 per cent, P=0.04).

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