The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Direct oral feeding following minimally invasive esophagectomy (NUTRIENT II trial). An international, multicenter, open-label randomized controlled trial. Ann Surg 2020; 271: 41-47

Published: 5th March 2020

Authors: Berkelmans GH, Fransen LFC, Dolmans-Zwartjes ACP, Kouwenhoven EA, van Det MJ, Nilsson M et al.


Some 132 patients were randomized to immediate oral feeding, or tube feeding for the first five days. Anastomotic leaks occurred in 18.5 and 16.4 per cent, respectively. Other complication rates and functional recovery were similar between the groups.

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