The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Double oral esomeprazole after a 3-day intravenous esomeprazole infusion reduces recurrent peptic ulcer bleeding in high-risk patients: a randomised controlled study. Gut 2014; 63: 1864-1872.

Published: 24th February 2015

Authors: Cheng HC, Wu CT, Chang WL, Cheng WC, Chen VVY, Sheu BS et al.

Conclusion

Patients at high risk (Rockall score of 6 or more) had a lower risk of rebleeding if they received the higher dose of oral esomeprazole (P<0.02).

Pubmed Link