This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Economic impact of routine cavity margins versus standard partial mastectomy in breast cancer patients: results of a randomized controlled trial. Ann Surg 2017; 265: 39-44.

Published: 1st March 2017

Authors: Chagpar AB, Horowitz NR, Killelea BK, Tsangaris T, Longley P, Grizzle S et al.

Conclusion

Some 235 women were included in the study. Although initial costs were higher in the cavity margin shave group due to longer operations and more pathology, by 90 days the costs were similar, as fewer women in this group required reoperation: 10.9 versus 27.6 per cent, P<0.01.

Pubmed Link

You may also be interested in

Scientific Surgery

Resection of cavity shave margins in stage 0–III breast cancer patients undergoing breast conserving surgery. A prospective multicenter randomized controlled trial. Ann Surg 2021; 273: 876-881.

Authors: Dupont E, Tsangaris T, Garcia-Cantu C, Howard-McNatt M, Chiba A, Berger AC et al.

Scientific Surgery

Early complications in delayed breast reconstruction: A prospective, randomized study comparing different reconstructive methods in radiated and non-radiated patients. Eur J Surg Oncol 2020; 46: 2208-2217.

Authors: Brorson F, Thorarinsson A, Kolby L, Elander A, Hansson E

Scientific Surgery

A network meta-analysis of surgical treatment in patients with early breast cancer. J Natl Cancer Inst 2019; 111: 903-915

Authors: Gui Y, Liu X, Chen X, Yang X, Li S, Pan Q et al.

Scientific Surgery

Preoperative breast magnetic resonance imaging in women with local ductal carcinoma in situ to optimize surgical outcomes: results from the randomized phase III trial, IRCIS. J Clin Oncol 2019; 37: 885-892

Authors: Balleyguier C, Dunant A, Ceugnart L, Kandel M, Chauvet M-P, Cherel P et al.

Scientific Surgery

Recurrence of breast cancer after regional or general anaesthesia: a randomized controlled trial. Lancet 2019; 394: 1807-1815

Authors: Sessler DI, Pei L, Huang Y, Fleischmann E, Marhofer P, Kurz A et al.

Scientific Surgery

Implant based breast reconstruction with acellular dermal matrix safety data from an open-label, multicenter, randomized, controlled trial in the setting of breast cancer treatment. Ann Surg 2019; 269: 836-841.

Authors: Lohmander F, Lagergren J, Roy P, Johansson H, Brandberg Y, Eriksen C et al.

Scientific Surgery

Axillary dissection versus no axillary dissection in patients with breast cancer and sentinel-node micrometastases (IBCSG 23-01): 10-year follow-up of a randomised, controlled phase 3 trial. Lancet Oncol 2018; 19: 1385-1393.

Authors: Galimberti V, Cole BF, Viale G, Veronesi P, Vicini E, Intra M et al.

Scientific Surgery

Quality of life and patient satisfaction after one-stage implant-based breast reconstruction with an acellular dermal matrix versus two-stage breast reconstruction (BRIOS): primary outcome of a randomised, controlled trial. Lancet Oncol 2018; 19: 1205-1214.

Authors: Negenborn VL, Yooung-Afat DA, Dikmans REG, Smit JM, Winters HAF, Don Griot JPW et al.

Scientific Surgery

Prospective randomized trial of use of in-house prepared low-cost radiopharmaceutical versus commercial radiopharmaceutical for sentinel lymph node biopsy in patients with early stage invasive breast cancer. World J Surg 2018; 42: 1391-1395.

Authors: Agarwal G, Rajan S, Mayilvaganan S, Mishra A, Krishnani N, Gambhir S et al.

Scientific Surgery

Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla – Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial. EJSO 2017; 43: 672-679.

Authors: Sávolt A, Péley G, Polgár C, Udvarhelyi N, Rubovszky G, Kovács E et al.

Scientific Surgery

Intraoperative ultrasound guidance in breast-conserving surgery shows superiority in oncological outcome, long-term cosmetic and patient-reported outcomes: Final outcomes of a randomized controlled trial (COBALT). EJSO 2017; 43: 649-657.

Authors: Volders JH, Haloua MH, Krekel NMA, Negenborn VL, Kolk RHE, Lopes Cardozo AMF et al.

Scientific Surgery

Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis. The ACOSOG Z0011 (Alliance) randomized clinical trial. JAMA 2017; 318: 918-926.

Authors: Giuliano AG, Ballman KV, McCall L, Beitsch P, Brennan MB, Keleman PR et al.