This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of abdominal ultrasound on clinical care, outcomes, and resource use among children with blunt torso trauma. A randomized clinical trial. JAMA 2017; 317: 2290-2296.

Published: 6th October 2017

Authors: Holmes JF, Kelley KM, Wootton-Gorges SL, Utter GH, Abramson LP, Rose JS et al.

Conclusion

Some 925 children were studied. FAST ultrasound did not reduce the need for CT, shorten stay in the emergency department, or affect overall hospital cost.

Pubmed Link

You may also be interested in

Scientific Surgery

Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury. A double-blind, placebo-controlled, randomized clinical trial. JAMA Surg 2020; 156: 11-20.

Authors: Guyette FX, Brown JB, Zenati MS, Early-Young BJ, Adams PW, Eastridge BJ et al.

Scientific Surgery

Effect of prophylactic embolization on patients with blunt trauma at high risk of splenectomy. A Randomized Clinical Trial. JAMA Surg 2020; 155: 1102-1111.

Authors: Arvieux C, Frandon J, Tidadini F, Monnin-Bares V, Foote A, Dubuisson V et al.

Scientific Surgery

A novel immune modulator for patients with necrotizing soft tissue infections (NSTI). Results of a multicenter, phase 3 randomized controlled trial of Reltecimod (AB 103). Ann Surg 2020; 272: 469-478.

Authors: Bulger E, May K, Robinson BR, Evans DC, Henry S, Green J et al.

Scientific Surgery

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomized, placebo-controlled trial. Lancet 2019; 394: 1713-1723

Authors: The CRASH-3 Trial Collaborators

Scientific Surgery

Plasma-first resuscitation to treat haemorrhagic shock during emergency ground transportation in an urban area: a randomised trial. Lancet 2018; 392: 283-291.

Authors: Moore HB, Moore EE, Chapman MP, McVaney K, Silliman CC, Banerjee A et al.

Scientific Surgery

Prehospital plasma during air medical transport in trauma patients at risk for hemorrhagic shock. N Engl J Med 2018; 379: 315-326.

Authors: Sperry JS, Guyette FX, Brown JB, Yazer MH, Triulzi DJ, Early-Young BJ et al.

Scientific Surgery

Randomized controlled trial evaluating the efficacy of peritoneal resuscitation in the management of trauma patients undergoing damage control surgery. J Am Coll Surg 2017; 224: 396–404.

Authors: Smith JW, Matheson PJ, Franklin GA, Harbrecht BG, Richardson DJ, Garrison RN et al.

Scientific Surgery

Immediate total-body CT scanning versus conventional imaging and selective CT scanning in patients with severe trauma (REACT-2): a randomised controlled trial. Lancet 2016; 388: 673-683.

Authors: Sierink JC, Treskes K, Edwards MJR, Beuker BJA, den Hartog D, Hohmann J et al.

Scientific Surgery

Transfusion of cryopreserved packed red blood cells is safe and effective after trauma: a prospective randomized trial. Ann Surg 2015; 262: 426–433.

Authors: Schreiber M, McCully B, Holcomb JB, Robinson BR, Minei JP, Stewart R et al. et al.

Scientific Surgery

Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma. The PROPPR randomized clinical trial. JAMA 2015; 313: 471-482.

Authors: Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM et al. et al.

Scientific Surgery

Whole body computed tomographic scanning leads to better survival as opposed to selective scanning in trauma patients: a systematic review and meta-analysis. J Trauma Acute Care Surg 2014; 77: 534-539.

Authors: Caputo ND, Stahmer C, Lim G, Shah K

Scientific Surgery

Results of a prospective randomized controlled study of the use of carboxymethylcellulose sodium hyaluronate adhesion barrier in trauma open abdomens. Surgery 2014; 156: 419-430.

Authors: Stawicki SP, Green JM, Martin ND, Green RH, Cipolla J, Seamon MJ et al. et al.