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Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis. The ACOSOG Z0011 (Alliance) randomized clinical trial. JAMA 2017; 318: 918-926.

Published: 5th January 2018

Authors: Giuliano AG, Ballman KV, McCall L, Beitsch P, Brennan MB, Keleman PR et al.


At median follow-up of 9.3 years, the addition of axillary dissection did not improve disease-free (0.85, 95 per cent confidence interval 0.62 to 1.17) or overall survival (0.85, 0 to 1.16) in this study that included 891 women.

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