This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of cephalexin plus trimethoprim-sulfamethoxazole vs cephalexin alone on clinical cure of uncomplicated cellulitis. A randomized clinical trial. JAMA. 2017; 317: 2088-2096.

Published: 14th June 2017

Authors: Moran GJ, Krishnadasan A, Mower WR, Abrahamian FM, LoVecchio F, Steele MT et al.

Conclusion

The addition of trimethoprim-sulfamethoxazole did not improve the clinical cure rate (83.5 per cent versus 85.5 per cent with cehpalexin alone) in this study that included 500 patients.

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