This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of 3 to 5 years of scheduled CEA and CT follow-up to detect recurrence of colorectal cancer. The FACS randomized clinical trial. JAMA 2014; 311: 263-270.

Published: 18th December 2014

Authors: Primrose JN, Perera R, Gray A, Rose P, Fuller A, Corkhill A et al. et al.

Conclusion

This study included 1202 patients randomized to one of four groups. Intensive follow-up with CT and regular blood testing for CEA increased the number of patients retreated for recurrence with curative intent. Overall mortality after a mean 4.4 years was similar in the minimum follow-up group (15.9 per cent) compared to all intensive follow-up groups (18.2 per cent).

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A randomized Phase II trial of adjuvant hepatic arterial infusion and systemic therapy with or without panitumumab after hepatic resection of KRAS wild-type colorectal cancer. Ann Surg 2021; 274: 248-254.

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Surgical management of idiopathic perianal fistulas: a systematic review and meta-analysis. Dig Surg 2021; 38: 104-119.

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Long-term outcomes of a randomized controlled trial of single-incision versus multi-port laparoscopic colectomy for colon cancer. Ann Surg 2021; 273: 1060-1065.

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Authors: Balvardi S, Pecorelli N, Castelino T, Niculiseanu P, Alhashemi M, Liberman AS et al.