Effect of early surgery vs endoscopy-first approach on pain in patients with chronic pancreatitis. The ESCAPE randomized clinical trial. JAMA 2020; 323: 237-247
Published: 20th March 2020
Authors: Issa Y, Kempeneers MA, Bruno MJ, Fockens P, Poley J-W, Ali UA et al.
Conclusion
Eighty-eight patients with painful chronic pancreatitis were included and followed for 18 months. Patients randomized to early surgical drainage procedures had less chronic pain (P=0.02). Complete or partial pain relief was experienced by 58 per cent after surgery versus 39 per cent in controls, P=0.01.
Pubmed LinkYou may also be interested in
Scientific Surgery
Authors: Mueck K, Wei S , Pedroza C , Bernardi K , Jackson ML , Liang MK et al.
Scientific Surgery
Authors: Van Dijk SM, Hallensleben NDL, van Santvoort HC, Fockens P, van Goor H, Bruno MJ et al.
Scientific Surgery
Authors: Van Brunschot S, van Grinsven J, van Santvoort HC, Bakker OJ, Besselink MG, Boermeester MA et al.
Scientific Surgery
Authors: Räty S, Pulkkinen J, Nordback I, Sand J, Victorzon M, Grönroos J et al. et al.
Scientific Surgery
Authors: Da Costa DW, Bouwense SA, Schepers NJ, Besselink MG, van Santvoort HC, van Brunschot S et al for the Dutch Pancreatitis Study Group et al.
Scientific Surgery
Authors: Rammohan A, Sathyanesan J, Rajendran K, Pitchaimuthu A, Perumal S, Balaraman K et al. et al.
Scientific Surgery
Authors: Bakkar OJ, van Brunschot S, van Santvoort HC, Besselink MG, Bollen TL, Boermeester MA et al. et al.
Scientific Surgery
Authors: Elmunzer BJ, Scheiman JM, Lehman GA, Chak A, Mosier P, Higgins PDR et al. et al.
Scientific Surgery
Authors: Bakker OJ, van Santvoort HC, van Brunschot S, Geskus RB, Besselink MG, Bollen TL et al. et al.
Scientific Surgery
Authors: Yao L, Huang X, Shi R, Zhang G.
Scientific Surgery
Authors: Z, Petrov MS, Xu J, Shanbhag S, Windsor JA, Pang S. et al.
Scientific Surgery
Authors: Van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH et al. et al.