This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of fish oil supplementation on graft patency and cardiovascular events among patients with new synthetic arteriovenous hemodialysis grafts. A randomized controlled trial. JAMA 2012; 307: 1809–1816.

Published: 12th November 2012

Authors: Lok CE, Moist L, Hemmelgam BR, Tonelli M, Vazquez MA, Dorval M et al.

Conclusion

Fish oil did not affect the composite primary endpoint of ‘graft thrombosis or radiological or surgical intervention over twelve months’ in this study that included 196 patients: relative risk 0.78, 95 per cent confidence interval 0.6 to 1.03, P=0.06. It did reduce the rate of dialysis graft failure: 0.58, 0.44 to 0.75, P<0.001.

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