Effect of multimodal prehabilitation vs postoperative rehabilitation on 30-day postoperative complications for frail patients undergoing resection of colorectal cancer. A randomized clinical trial. JAMA Surg 2020; 155: 233-242.
Published: 17th November 2020
Authors: Carli F, Bousquet-Dion G, Awasthi R, Elsherbini N, Liberman S, Boutros M et al.
Some 110 frail patients were randomized in this trial of preoperative or postoperative multimodal rehabilitation. Complication rates after surgery were similar at 30 days and there were no differences in any other secondary outcome measures including hospital stay and patient reported outcomes.Pubmed Link
You may also be interested in
The ALCCaS Trial: a randomized controlled trial comparing quality of life following laparoscopic versus open colectomy for colon cancer. Dis Colon Rectum 2018; 61: 1156-1162.
Authors: McCombie AM, Frizelle F, Bagshaw PF, Frampton CM, Hewett PJ, McMurrick PJ et al.
Enhanced recovery protocols for adults undergoing colorectal surgery. A systematic review and meta-analysis. Dis Colon Rectum 2018; 61: 1108-1118.
Authors: Greer NL, Gunnar WP, Dahm P, Lee AE, MacDonald R, Shaukat A et al.
Effect of more vs less frequent follow-up testing on overall and colorectal cancer–specific mortality in patients with stage II or III colorectal cancer. The COLOFOL Randomized Clinical Trial. JAMA 2018; 319: 2095-2103.
Authors: Wille-Jørgensen P, Syke I, Smedh K, Laurberg S, Nielsen DT, Petersen SH et al.
Ensuring early mobilization within an enhanced recovery program for colorectal surgery: a randomized controlled trial. Ann Surg 2017; 266: 223-231.
Authors: Fiore JF Jr, Castelino T, Pecorelli N, Niculiseanu P, Balvardi S, Hershorn O et al.
Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial. Lancet 2017; 389: 1218–1228.
Authors: Paramsothy S, Kamm MA, Kaakoush NO, Walsh AJ, van den Bogaerde J, Samuel D et al.
Oral and parenteral versus parenteral antibiotic prophylaxis in elective laparoscopic colorectal surgery (JMTO PREV 07–01): a phase 3, multicenter, open-label, randomized trial. Ann Surg 2016; 263: 1085-1091.
Authors: Hata H, Yamaguchi T, Hasegawa S, Nomura A, Hida K, Nishitai R et al.
Effect of 3 to 5 years of scheduled CEA and CT follow-up to detect recurrence of colorectal cancer. The FACS randomized clinical trial. JAMA 2014; 311: 263-270.
Authors: Primrose JN, Perera R, Gray A, Rose P, Fuller A, Corkhill A et al. et al.
Authors: Wagner EH, Ludman EJ, Aiello Bowles EJ, Penfold R, Reid RJ, Rutter CM et al.
Randomized phase III trial exploring the use of long-acting release octreotide in the prevention of chemotherapy-induced diarrhea in patients with colorectal cancer : The LARCID Trial. J Clin Oncol 2014; 32: 1006-1011.
Authors: Hoff PM, Saragiotto DF, Barrios H, del Giglio A, Coutinho AK, Andrade AC et al. et al.
Multicentre randomized trial of centralised nurse-led telephone-based care coordination to improve outcomes after surgical resection for colorectal cancer: the CONNECT intervention. J Clin Oncol 2013; 31: 3585–3591.
Authors: Young JM, Butow PN, Walsh J, Durcinoska I, Dobbins TA, Rodwell L et al. et al.
Effects of a telephone-delivered multiple health behavior change intervention (CanChange) on health and behavioral outcomes in survivors of colorectal cancer: a randomized controlled trial. J Clin Oncol 2013; 31: 2313-2321.
Authors: Hawkes AL, Chambers SK, Pakenham KI, Patrao TA, Baade PD, Lynch BM et al. et al.
Questionnaire versus telephone follow-up to detect postdischarge complications in surgical patients: randomized clinical trial. World J Surg 2012; 36: 2576–2583.
Authors: Visser A, Ubbink DT, Gouma DJ, Goslings C