The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of oral capsule vs. colonoscopy-delivered fecal microbiota transplantation on recurrent Clostridium difficile infection. A randomized clinical trial JAMA 2017; 318: 1985-1993.

Published: 22nd February 2018

Authors: Kao D, Roach B, Silva M, Beck P, Rioux K, Kaplan GG et al.

Conclusion

Some 116 patients each received a single treatment. The risk of recurrent C diff was similar after 12 weeks: 2/53 after capsule and 2/52 after colonoscopy. Quality-of-life rates were also similar. Patients found the capsule method less unpleasant, P=0.01.

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