This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of a scalp cooling device on alopecia in women undergoing chemotherapy for breast cancer. The SCALP randomized clinical trial. JAMA 2017; 317: 596-605.
Published: 30th March 2017
Authors: Nangia J, Wang T, Osborne C, Niravath P, Otte K, Papish S et al.
Conclusion
The trial was stopped early after 142 women had been randomized. The trial endpoint (<50 per cent hair loss, not needing a wig) was reached by 50.5 per cent of cooled women, compared to none in the control group, P=0.0061.
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