The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Efficacy of cholestyramine ointment in reduction of postoperative pain and pain during defecation after open haemorrhoidectomy: results of prospective, single-centre, randomized, double-blind, placebo-controlled trial. World J Surg 2013; 37: 657–662.

Published: 10th January 2014

Authors: Ala S, Eshghi F, Enavatifard R, Fazel P, Rezaei B, Hadianamrei R et al.

Conclusion

Some 91 patients were included and randomized to cholestyramine ointment for 14 days after surgery or controls. The ointment reduced postoperative pain for 48h (P<0.001), analgesic requirement (P<0.001), and pain on defaecation (P=0.001).

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