This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Efficacy of preoperative oral antibiotic prophylaxis for the prevention of surgical site infections in patients with Crohn’s Disease. A Randomized Controlled Trial. Ann Surg 2019; 269: 420-426.

Published: 21st June 2019

Authors: Uchino M, Ikeuchi H, Bando T, Chohno T, Sasaki H, Horio Y et al.

Conclusion

The addition of oral antibiotics to intravenous antibiotic prophylaxis reduced the rate of surgical site infection from 27/162 (16.6 per cent) to 12/163 (7.4 per cent), P=0.01.

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