This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Efficacy of probiotics in irritable bowel syndrome: a meta-analysis of randomised, controlled trials Dis Colon Rectum 2008; 51: 1775-1780

Published: 1st January 2008

Authors: Nikfar S, Rahimi R, Rahimi F, Derakhshani S, Abdollahi M

Conclusion

Eight randomized trials were included in the analysis. Probiotics significantly improved symptoms: relative risk 1.22, 95 percent confidence interval 1.07 to 1.4, P=0.0042

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A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

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