This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Endoscopic regression of Barrett’s oesophagus during omeprazole treatment: a randomised double blind study. Gut 1999; 46: 489-94.

Published: 1st January 1999

Authors: Peters FTM, Ganesh S, Kuipers EJ, Sluiter WJ, Klinkenberg-Knol EC, Lamers CBHW et al. et al.

Conclusion

Sixty-eight patients were randomly allocated omeprazole or ranitidine. Ranitidine had no effect but omeprazole caused significant regression of Barrett's at endoscopy after 24 months

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